Chronic overlapping pain conditions (COPCs) refer to a set of chronic pain disorders that frequently co-occur and may involve partially overlapping mechanisms. The U.S. National Institutes of Health currently recognizes …
To review recent evidence on the association between progestin exposure and meningioma risk and to propose practical recommendations for hormonal management in women requiring progestin therapy.
Uterine leiomyomas are common benign tumors, but their clinical presentation can be misleading. We report two unusual cases of pedunculated uterine masses presenting with heavy vaginal bleeding. In the first …
The appendix is involved in a diverse spectrum of inflammatory, infectious, benign, and malignant conditions that extend far beyond acute appendicitis. Although acute appendicitis remains the most common appendiceal emergency, …
Endometriosis is characterized by a persistent inflammatory process and is commonly shown to be associated with pelvic pain, dysmenorrhea, and a deterioration in overall quality of life. Due to limitations …
Introduction Endometriosis is a common cause of infertility and affects reproductive outcomes through multiple mechanisms, including pelvic adhesions, altered pelvic anatomy, and inflammatory changes. The Endometriosis Fertility Index (EFI) was …
Endometrial dysfunction represents a central pathological factor underlying recurrent implantation failure and infertility. This review provides a comprehensive synthesis of the physiological basis of endometrial function, the pathological factors compromising …
Deep infiltrating endometriosis (DIE) is a severe form of endometriosis that rarely undergoes malignant transformation, and when it does, diagnosis is often difficult. Here, we report two cases of long-standing …
Perimenopause is a clinically distinct stage in which abnormal uterine bleeding, fibroids, adenomyosis, endometriosis, and adnexal pathology may require surgical evaluation. Management is complex because symptom burden and structural disease …
Natural bioactive compounds, such as curcumin, polyphenols, and flavonoids are important in the prevention and treatment of lifestyle disorders like diabetes, cancer, and heart disease. Their immunomodulatory, antiviral, antioxidant, and …