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A rare case of life-threatening haematochezia in pregnancy associated with decidualized rectal mucosal endometriosis.

To report and emphasize the difficulty in diagnosis and management of acute gastrointestinal bleeding due to recurrent endometriosis in pregnancy.

Published: July 22, 2026, midnight
The Molecular and Cellular Mechanisms of Melatonin: From Physiological Actions to Clinical Applications in Reproductive Medicine.

Melatonin has evolved from its classical role as a pineal-derived circadian regulator to a molecule increasingly recognized for its mitochondrial and cytoprotective functions. This review examines the molecular mechanisms and …

Published: July 22, 2026, midnight
Integrating single-cell and bulk transcriptomic perturbation resources reveals complementary therapeutic spaces for drug repurposing.

Transcriptome-based drug repurposing can accelerate therapeutic discovery, but is limited by fragmented resources, inconsistent quality control, and reliance on single perturbation databases. We developed CDRPipe ( C omputational D rug …

Published: July 22, 2026, midnight
Profiling miRNA in salivary samples from subjects with endometriosis: a pilot study.

Endometriosis is a common, chronic, estrogen-dependent gynecological disorder characterized by the growth of endometrial-like tissue outside the uterus and frequently associated with pelvic pain and infertility. Despite its high prevalence, …

Published: July 22, 2026, midnight
Integrative serum proteomic and metabolomic profiling in ovarian endometrioma: an exploratory multi-omics study.

Ovarian endometrioma (OEM) is a common manifestation of endometriosis and is associated with both local lesions and systemic alterations. While immune dysregulation and metabolic disturbances have been individually reported in …

Published: July 22, 2026, midnight
Endometriosis: surgical management for fertility enhancement.

Endometriosis is a common, chronic inflammatory condition characterized by the presence of endometrium-like tissue outside of the uterus that can impact fertility through multiple mechanisms. In this review, the diagnosis, …

Published: July 22, 2026, midnight
p53-mediated epigenetic regulation in the pathogenesis of endometriosis.

Endometriosis (EMs) is a common gynecological disorder affecting reproductive‑aged women, characterized by ectopic endometrial growth and chronic pelvic pain that severely impairs quality of life. Although its pathogenesis remains incompletely …

Published: July 21, 2026, midnight
Menopause and Endometriosis - Symptoms and Risk of Malignant Transformation: A Systematic Review of the Literature.

To review the evidence concerning the clinical presentation of endometriosis in postmenopausal women and the associated risk of malignant transformation.

Published: July 21, 2026, midnight
Integrative Transcriptomic Analysis Identifies a Key Candidate Gene Bridging Inflammation and DNA Repair in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue. Although retrograde menstruation is highly prevalent, only a subset of women develops the disease. This …

Published: July 21, 2026, midnight
Ovarian endometriosis associated with significantly elevated CA19-9: a case report.

Carbohydrate antigen 19-9 (CA19-9) is a well-established tumour marker primarily associated with pancreaticobiliary and gastrointestinal malignancies. Its elevation in benign gynaecological conditions, particularly in isolated ovarian endometriosis (OE) without malignancy, …

Published: July 21, 2026, midnight
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