Excessive activation of inflammatory responses and oxidative stress plays a critical role in the pathophysiology of endometriosis (EMs), which is characterized by ectopic lesion growth and chronic pelvic pain. However, …
Endometriosis (EMs) is increasingly recognized as a chronic inflammatory disease in which innate immune dysregulation plays an important role. Its immunopathological features include macrophage polarization imbalance, with M1-skewed activation in …
Brain-derived neurotrophic factor (BDNF) is essential for neuronal survival and development, and is also involved in oogenesis, follicle recruitment, and germ cell survival, which could impact reproduction. However, in humans, …
Endometriosis (EM) is a chronic inflammatory, estrogen‑dependent benign gynecological disorder. A subset of patients with EM may subsequently develop endometriosis‑associated ovarian cancer (EAOC), implying a biological continuum between these two …
Endometriosis is a chronic inflammatory disease characterised by pain, infertility and recurrence. Current pharmacological management relies largely on hormonal suppression, which can reduce pain and disease activity but does not …
Adenomyosis is a chronic gynecological condition associated with pain, abnormal uterine bleeding, and impaired fertility. However, little is known about the psychosocial experiences and coping strategies of individuals with adenomyosis …
Infertility is a major reproductive health problem with significant social, psychological, and economic consequences. In Nigeria, cultural expectations surrounding childbearing may intensify stigma and emotional distress, particularly among women. This …
The term 'endometrosis', coined in 1992 to describe chronic degenerative changes of the equine endometrium, is descriptively imprecise and readily confused with 'endometritis' and the human gynaecological condition 'endometriosis'. A …
Endometriosis, a chronic health condition primarily associated with women, is not just a physical experience but is an invisible, gendered illness deeply intertwined with societal narratives that often overlook women's …