Oxidative stress, defined as an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, plays a critical role in female reproductive health, particularly in ovarian function. This review provides …
Women remain underrepresented in clinical drug development despite their unique biological characteristics and growing disease burden. In China, this disparity is particularly concerning given the rising incidence of gynecologic conditions …
Endometriosis is a chronic, estrogen-dependent inflammatory disease defined by the presence of endometrial-like tissue outside the uterus, affecting approximately 10% of women of reproductive age as well as a notable …
Endometriosis, a chronic inflammatory disease affecting 10-15% of women of reproductive age, remains a leading cause of female subfertility. While current management strategies focus on surgical excision and hormonal suppression, …
Endometriosis is a chronic inflammatory disease affecting approximately 10% of women of reproductive age. Urinary tract involvement is rare, occurring in approximately 1-2% of cases, with the bladder being the …
Patient-derived organoids (PDOs) have emerged as physiologically relevant three-dimensional (3D) culture systems that closely mimic the molecular and histological features of the human endometrium and associated malignancies. Owing to their …
Diaphragmatic endometriosis (DiaE) is a frequently underdiagnosed manifestation of deep endometriosis (DE), typically occurring in patients with advanced pelvic disease. Accurate preoperative detection remains challenging, as standard laparoscopy may overlook …
Ovarian clear cell carcinoma (CCC) is a distinct histological subtype of epithelial ovarian cancer characterized by unique biological behavior and heterogeneous clinicopathological features. In contrast with other epithelial ovarian malignancies, …
Endometriosis is a debilitating chronic inflammatory disorder driven by extensive molecular reprogramming. Despite significant bench research into its pathogenesis, translating these molecular discoveries into clinical practices that improve patient outcomes …
Female-specific pain conditions such as dysmenorrhoea, endometriosis, and pain associated with pregnancy, childbirth, and menopause are highly prevalent and frequently impair quality of life. Superficial heat therapy (SHT) has long …