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The Therapeutic Role of Dienogest in Endometriosis-Associated Pain: From Basics to Clinics.

The most common symptom of endometriosis is pain. The pathogenesis of endometriosis-associated pain remains unclear. In this review, we illustrate the pathogenesis of endometriosis-associated pain and the mechanisms of dienogest …

Published: July 23, 2026, midnight
Relationship and mental health outcomes after childbirth among women with endometriosis: An 8-year follow-up study.

BackgroundTransitioning to parenthood is stressful for relationships. Women with endometriosis face several health challenges, which may further strain their relationships when they become parents. However, it remains uncertain whether this …

Published: July 22, 2026, midnight
The Molecular and Cellular Mechanisms of Melatonin: From Physiological Actions to Clinical Applications in Reproductive Medicine.

Melatonin has evolved from its classical role as a pineal-derived circadian regulator to a molecule increasingly recognized for its mitochondrial and cytoprotective functions. This review examines the molecular mechanisms and …

Published: July 22, 2026, midnight
Profiling miRNA in salivary samples from subjects with endometriosis: a pilot study.

Endometriosis is a common, chronic, estrogen-dependent gynecological disorder characterized by the growth of endometrial-like tissue outside the uterus and frequently associated with pelvic pain and infertility. Despite its high prevalence, …

Published: July 22, 2026, midnight
Integrative Transcriptomic Analysis Identifies a Key Candidate Gene Bridging Inflammation and DNA Repair in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue. Although retrograde menstruation is highly prevalent, only a subset of women develops the disease. This …

Published: July 21, 2026, midnight
Lower Urinary Tract Symptoms in Women with Surgically Confirmed Endometriosis: Association with Urethral Ultrasonographic Findings.

Background: Endometriosis is a chronic inflammatory disease affecting approximately 10% of women of reproductive age and is commonly associated with pelvic pain and infertility. Increasing evidence indicates that lower urinary …

Published: July 17, 2026, midnight
Symptoms and distress across the menstrual cycle in a representative sample of Austrian and German people who menstruate: A cross-sectional study.

BackgroundPeople who menstruate may experience a range of symptoms, which, fluctuating throughout the different cycle phases, can interfere with their normal functioning. To date, research mostly investigated pain and psychological …

Published: July 16, 2026, midnight
Rheumatic Heart Disease: Inflammation, Immune Pathways, Valve Remodeling, and the Promise of SGLT2 Inhibitors.

Rheumatic heart disease (RHD) remains the leading cause of acquired valvular heart disease in low- and middle-income countries, affecting an estimated 40 million individuals and disproportionately affecting children and young …

Published: July 16, 2026, midnight
N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence.

Endometriosis is a chronic inflammatory and estrogen-dependent disease in which oxidative stress, immune dysregulation, and lesion-supportive microenvironmental signaling contribute to lesion development. N-acetylcysteine (NAC), a glutathione-replenishing and redox-modulating agent, has …

Published: July 16, 2026, midnight
FOS and Other Genes Linked to Oxidative Stress Are Upregulated in Women Suffering from Endometriosis and Might Negatively Impact the Oocyte Developmental Competence During ICSI.

We aim to elucidate the impact of endometriomas on oocyte developmental competence and identify genetic alterations that may influence ICSI success rates in women of different ages.

Published: July 16, 2026, midnight
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