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H3K27me3-mediated epigenetic regulation of TET1 in the eutopic endometrium of women with endometriosis and infertility.

Endometriosis is a common gynecological condition associated with chronic inflammation, epigenetic dysregulation, and infertility. The TET1 gene, involved in DNA demethylation, may be regulated by repressive histone modifications such as …

Published: Aug. 10, 2025, midnight
Clinical Characteristics of Endometriosis with and without Dysmenorrhea Diagnosed by Laparoscopy - Frontiers

Clinical Characteristics of Endometriosis with and without Dysmenorrhea Diagnosed by Laparoscopy Frontiers

Published: Aug. 6, 2025, 10:26 p.m.
Intraoperative care and complications of symptomatic adolescent and young adult patients undergoing laparoscopy to diagnose and/or to treat endometrioses: A Multi-Institutional Review.

This multi-institutional, retrospective study explores the risks of laparoscopy for diagnosis and treatment of endometriosis to facilitate shared medical decision-making in patients age < 22 years old with chronic pain …

Published: Aug. 6, 2025, midnight
Correlation of Sonographic and Intraoperative Findings of Deep-Infiltrating Endometriosis.

Endometriosis is a chronic inflammatory condition affecting approximately 5%-10% of reproductive-aged women. Transvaginal ultrasound (TVUS) is increasingly used to diagnose deep-infiltrating endometriosis (DIE). This study assesses the sonographic accuracy of …

Published: Aug. 6, 2025, midnight
Laparoscopic ovarian drilling (LOD) versus Step-up gonadotropin therapy in infertile anovulatory PCOS women resistant to sequential letrozole and gonadotropin-based ovulation induction cycles: a randomized controlled trial.

To study the effect of laparoscopic ovarian drilling (LOD) versus step-up gonadotropin therapy on follicular response in infertile anovulatory PCOS women resistant to sequential Letrozole + HMG (Human Menopausal Gonadotropin) …

Published: Aug. 2, 2025, midnight
Can the MMP-9/NGAL ratio be a diagnostic biomarker for the diagnosis of endometrioma in infertile patients?

In this study, we aimed to investigate whether serum NGAL, MMP-9 and the MMP-9/NGAL ratio, which are inflammatory markers used for the diagnosis and follow-up of some diseases, can be …

Published: July 30, 2025, midnight
Advances in non-invasive diagnostic tools for endometriosis: A narrative review of the past ten years.

Endometriosis is a chronic condition defined by endometrium-like tissue outside the uterus, with symptoms including pain, infertility, and fatigue. Despite the high prevalence of disease, diagnosis is frequently delayed, in …

Published: July 29, 2025, midnight
Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs.

Endometriosis is highly underdiagnosed and undertreated gynecological disorder, with diagnosis often delayed by 8-12 years. This delay can have serious consequences including infertility. Currently, the gold standard for endometriosis diagnosis …

Published: July 28, 2025, midnight
The Role of MRI in Diagnosis and Pre-Surgical Mapping of Endometriosis.

Endometriosis is a chronic multisystem disease caused by the presence of endometrium-like tissue outside the endometrial canal, inciting inflammation and fibrosis. Transvaginal ultrasound (TVUS) and MRI have replaced diagnostic laparoscopy …

Published: July 28, 2025, midnight
Laparoscopic mesentery-sparing NOSE bowel resection for endometriosis: when and how?

To describe the peri-operative considerations and surgical steps for a laparoscopic segmental resection for colorectal endometriosis, using a nerve-sparing, mesentery-sparing, and natural orifice specimen extraction (NOSE) technique.

Published: July 26, 2025, midnight
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