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Revisiting the role of danazol in the contemporary management of endometriosis-related pain: a systematic review.

Danazol is a synthetic steroid approved in 1976 for the treatment of endometriosis-associated pain. Despite its established efficacy, its clinical use has markedly declined due to androgenic and metabolic adverse …

Published: Aug. 28, 2026, midnight
Selected gynecologic MRI mimics and pitfalls: practical problem-solving pearls.

Pelvic magnetic resonance imaging (MRI) plays an important role in the evaluation of suspected gynecologic malignancies, providing high soft tissue contrast and multiparametric capabilities, including diffusion-weighted imaging and dynamic contrast …

Published: Aug. 28, 2026, midnight
Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care.

Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances …

Published: Aug. 28, 2026, midnight
Prevalence of sexual dysfunction in patients with endometriosis: a systematic review and meta-analysis.

To systematically assess the prevalence of sexual dysfunction among patients suffering from endometriosis.

Published: Aug. 27, 2026, midnight
Lack of socio-demographic participant diversity in endometriosis evidence risks unrepresentative clinical guidance: a structured review of a NICE guideline.

Published: Aug. 27, 2026, midnight
Single-stapled versus double-stapled colorectal anastomosis after anterior resection: Systematic review and meta-analysis of short-term and functional outcomes.

The double-stapled anastomosis technique is widely considered the standard approach for colorectal anastomosis after anterior rectal resection. Recently, the single-stapled anastomosis technique has gained attention because it may reduce potential …

Published: Aug. 26, 2026, midnight
ATP-P2X3 Signaling as a Shared Neural Sensitization Pathway in Endometriosis and Irritable Bowel Syndrome: Mechanisms and Therapeutic Implications.

Endometriosis and irritable bowel syndrome (IBS) are chronic pain disorders that frequently coexist and share key pathophysiological features, including neuroinflammation, visceral hypersensitivity, peripheral sensitization, and central sensitization. Emerging evidence suggests …

Published: Aug. 25, 2026, midnight
Postmenopausal endometriosis: current evidence and clinical challenges in diagnosis and treatment.

Endometriosis was once thought to affect only reproductive-aged women. However, 2-5% of postmenopausal individuals remain affected. Guidance for this group is limited. This review outlines an updated approach to postmenopausal …

Published: Aug. 24, 2026, midnight
A systematic review of restorative reproductive medicine practices.

To determine if RRM is associated with improved live birth compared to no treatment or standard of care.

Published: Aug. 21, 2026, midnight
Endothelial cell heterogeneity drives angiogenesis in endometriosis: mechanisms and emerging organoid-based models.

Endometriosis (EMs) is characterized by the establishment and persistence of ectopic lesions, a process fundamentally dependent on aberrant angiogenesis. Endothelial cells (ECs) play a central role in this process; however, …

Published: Aug. 20, 2026, midnight
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