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Exploring the Role of MicroRNAs in Progesterone and Estrogen Receptor Expression in Endometriosis.

Background/Objectives: Patients with endometriosis still respond poorly to progestins due to progesterone resistance associated with microRNAs (miRNAs). The aim of this study was to investigate the expression of selected miRNAs, …

Published: Sept. 28, 2024, midnight
Nonsurgical approaches to the diagnosis and evaluation of endometriosis.

An inability to make the diagnosis of endometriosis or evaluate lesion response to treatment without surgery is a clear impediment to understanding the disease and to developing new therapies. The …

Published: Dec. 15, 2023, midnight
Machine learning-based integrated identification of predictive combined diagnostic biomarkers for endometriosis.

Background: Endometriosis (EM) is a common gynecological condition in women of reproductive age, with diverse causes and a not yet fully understood pathogenesis. Traditional diagnostics rely on single diagnostic biomarkers …

Published: Nov. 27, 2023, midnight
External validation of putative biomarkers in eutopic endometrium of women with endometriosis using NanoString technology.

To combine different independent endometrial markers to classify the presence of endometriosis.

Published: Oct. 9, 2020, midnight
Validation of Laser Capture Microdissection Protocol in Endometriosis Studies.

Background and Objectives: The presence of endometrial-like tissue outside the uterine cavity is a key feature of endometriosis. Although endometriotic lesions appear to be histologically quite similar to the eutopic …

Published: Aug. 22, 2019, midnight
Technical Verification and Assessment of Independent Validation of Biomarker Models for Endometriosis.

There is a great need for a noninvasive diagnosis for endometriosis. Several biomarkers and biomarker panels have been proposed. Biomarker models consisting of CA-125, VEGF, Annexin V, and glycodelin/sICAM-1 were …

Published: July 25, 2019, midnight
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