Latest Articles

Risk, prevalence and survival outcomes of ovarian cancer in women with endometriosis: the ENDOCANCER systematic review and meta-analysis.

Endometriosis is linked to an increased risk of epithelial ovarian cancer (EOC), especially clear cell and endometrioid subtypes. The extent and prognostic significance of this link are still not fully …

Unveiling the Bidirectional Relationship on the Effect of Gut Microbiota and Female Infertility: A Narrative Review.

Dysbiosis is the substitution of the normal gut flora with a dysfunctional array of organisms that influences the outcome of multiple inflammatory pathways, contributing to systemic inflammation and various disease …

Targeting TLR4 Attenuates Endometriosis Progression by Suppressing NF-κB/NLRP3 Inflammasome Activation and Angiogenesis.

Endometriosis is a chronic inflammatory disorder affecting approximately 10% of reproductive-age women, yet non-hormonal therapeutic options remain limited. This study investigates the role of the TLR4/NF-κB/NLRP3 inflammasome axis in endometriosis …

Retraction: Case-control study to develop and validate a questionnaire for the secondary prevention of endometriosis.

Differential Antioxidant Capacities of Human Endometriotic and Endometrial Cell Models Under H2O2 Exposure.

Endometriosis is associated with oxidative stress and debilitating symptoms, yet its pathophysiology remains incompletely understood, and current treatments are still limited. In this study, oxidative stress responses were compared in …

Endometriosis Uncovered: From Chronic Inflammation to Reproductive Dysfunction and Impaired ART Outcomes.

Background and Objectives: Endometriosis is a chronic, estrogen-dependent disorder characterized by the presence of functional endometrial tissue, comprising both glandular and stromal components, located outside the uterine cavity, affecting approximately …

Interpretations of Menstrual Blood Appearance and Diagnostic Potential Among Social Media Users: Cross-Sectional Mixed Methods Social Media Listening Study.

Menstruation has long been framed primarily as a hygiene issue, with mainstream products and public messaging emphasizing concealment and disposal of menstrual blood (MB). This has contributed to a culture …

The paradoxical association between endometrioma size and serum anti-Müllerian hormone levels in infertile women.

The impact of endometrioma size on ovarian reserve remains controversial. Although endometriomas are known to reduce anti-Müllerian hormone (AMH) levels, some studies suggest a paradoxical association between larger cysts and …

Electroacupuncture ameliorates Endometriosis-Associated ovarian dysfunction by activating Nrf2 pathway to upregulate GPX4 function and inhibiting ferroptosis.

Endometriosis (EMs) is a common cause of ovarian dysfunction and infertility, closely linked to iron overload-induced oxidative stress and ferroptosis. While electroacupuncture (EA) has shown promise in treating reproductive disorders, …

Endometriosis, subclinical cardiac remodeling, and cardiovascular risk: mechanistic insights from cardiac magnetic resonance and mediation analysis.

Endometriosis is a systemic gynecological disorder affecting ~ 10% of reproductive-aged women and shares pathophysiological features with cardiovascular disease (CVD). However, its associations with cardiac remodeling and CVD risk, as …