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The Reproductive Tract Microbiome and Female Fertility: Dysbiosis, Disease Links, and Emerging Therapeutic Strategies.

The reproductive tract microbiome plays a pivotal role in female fertility, with Lactobacillus-dominated communities maintaining a protective, low-pH environment. Dysbiosis-characterized by a reduction in Lactobacillus species and overgrowth of anaerobes-is …

Published: Jan. 21, 2026, midnight
Intestinal Stenosis Secondary to Grade IV Endometriosis: A Case Report.

Intestinal stenosis secondary to deep endometriosis grade four is an uncommon presentation that often leads to delayed diagnosis and challenging therapeutic decisions. We report the case of a 41-year-old woman …

Published: Jan. 21, 2026, midnight
The evolution of endometriosis research models: a paradigm shift from immortalized cell lines to organoids†.

Endometriosis is a complex condition affecting 10% of reproductive-age women worldwide, yet its study has long been hindered by the shortcomings of traditional research models. This review aims to propose …

Published: Jan. 19, 2026, midnight
Validation of the deep pelvis endometriosis index (dPEI) to evaluate surgical outcomes of robotic-assisted surgery for endometriosis.

The Deep Pelvic Endometriosis Index (dPEI) is a preoperative MRI-based score initially validated to predict surgical outcomes in patients undergoing laparoscopic treatment for deep pelvic endometriosis (DPE). Its applicability in …

Published: Jan. 19, 2026, midnight
The iron-ferroptosis axis in bone homeostasis: a potential complementary pathway for osteoporosis in endometriosis.

Endometriosis, a chronic gynecological disorder, is clinically associated with an increased risk of osteoporosis. While this link has been primarily attributed to hypoestrogenism resulting from the disease process or its …

Published: Jan. 19, 2026, midnight
Characteristics and Preoperative Management of Adolescent Patients With Pathology-Confirmed Endometriosis: A Multi-Institutional Study.

Endometriosis affects an estimated 25% to 75% of adolescent patients with chronic pelvic pain; the diagnosis is made surgically and treatment typically consists of hormone suppression and pain management strategies. …

Published: Jan. 19, 2026, midnight
Cholesterol granuloma forming the solid components within an endometrioma showing intense FDG uptake, mimicking malignancy: A case report.

A mural solid component (SC) within an endometrioma (ovarian endometriotic cyst), demonstrating internal vascularity or increased fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET), is considered a characteristic finding suggestive …

Published: Jan. 19, 2026, midnight
Associations of VEGF and CA125 with disease stage and pain among women with endometriosis: A cross-sectional study in Indonesia.

Endometriosis is a chronic gynecological disease characterized by the presence of endometrial tissue outside the uterine cavity, affecting approximately 10% of women of reproductive age. Vascular endothelial growth factor (VEGF) …

Published: Jan. 19, 2026, midnight
[Laparoscopic Resection of an Ectopic Endometriosis-Associated Carcinoma Arising in the Rectum-A Case Report].

A woman in her seventies presented with mucous hematochezia. Colonoscopy revealed a poorly differentiated adenocarcinoma in the upper rectum. Immunohistochemical staining showed CK7 positivity and CK20/CDX2 negativity, findings atypical for …

Published: Jan. 18, 2026, midnight
Opioid-sparing by low-dose ketamine for endometriosis surgery. A single-center, prospective, randomized, trial.

Endometriosis affects 10% of women of childbearing age and 25-50% of infertile women worldwide. Although most patients with endometriosis are completely asymptomatic, there is still a significant proportion of patients, …

Published: Jan. 18, 2026, midnight
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