Central sensitization (CSS), a condition where the central nervous system amplifies pain signals, may impact response to treatment of chronic pain conditions. The objective of this study is to determine …
Ectopic pancreas (EP) is most commonly located in the upper gastrointestinal tract, particularly in the stomach. Malignant transformation of EP is exceptionally rare, and due to its very low incidence, …
Lipedema is a chronic, estrogen-sensitive adipose tissue disorder characterized by disproportionate subcutaneous fat accumulation, fibrosis, inflammation, and resistance to fat mobilization. Despite its high prevalence, lipedema remains poorly understood and …
Endometriosis is a prevalent gynecological disorder that is estimated to affect approximately 10% of women of childbearing age globally. However, the condition remains significantly under-or misrecognized, and the mean time …
Endometriosis, while commonly managed by gynecologists, is rarely encountered by general surgeons and is often identified incidentally or upon histopathological examination. This condition can manifest in both pelvic and extrapelvic …
This review explores the dual role of reactive oxygen species (ROS) and free radicals in the pathogenesis of endometriosis, aiming to deepen our understanding of these processes through a systematic …
The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signalling pathway regulates cell metabolism, inflammation and the immune response. This signalling pathway is essential for maintaining reproductive homeostasis and influencing steroidogenesis, implantation, …
Endometriosis is a chronic, estrogen-dependent inflammatory condition that affects multiple organ systems and significantly impairs the quality of life in women of reproductive age. While conventional hormonal therapies may alleviate …
Immunological factors appear to play an important role in the development of endometriosis, as evidenced by the aberrant functioning of immune cells often observed in affected women. Although endometriosis is …
Background: Endometriosis is a complex, estrogen-dependent condition that can significantly impact women's quality of life and fertility. Current diagnostic strategies remain invasive and often prolonged, demonstrating the need for reliable, …