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Single-cell and spatially resolved omics reveal transcriptional and metabolic signatures of ovarian endometriomas.

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of ovarian endometriomas …

Published: Nov. 22, 2025, midnight
Efficacy of Dienogest Versus GnRH Agonists After Endometriosis Surgery: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis compared the efficacy of dienogest (DNG) and gonadotropin-releasing hormone (GnRH) agonists in the management of endometriosis-related symptoms following surgical intervention, their related adverse effects, and …

Published: Nov. 22, 2025, midnight
Venous Thromboembolism Risk Associated With Relugolix-estradiol-norethisterone Acetate Combination Therapy.

Relugolix, an oral GnRH receptor antagonist, is effective in treating uterine myomas and endometriosis. However, concerns persist regarding the venous thromboembolism (VTE) risk associated with its combination with oral estradiol …

Published: Nov. 22, 2025, midnight
[Medicinal cake-separated moxibustion inhibits ectopic endometrium remodeling by regulating TGF-β/Smad signaling in rats with endometriosis].

To investigate the mechanism of medicinal cake-separated moxibustion in inhibiting the adhesion, invasion and angiogenesis of ectopic endometriotic tissues in endometriosis (EMs) rats through transforming growth factor-β1 (TGF-β)/Sma and Mad …

Published: Nov. 21, 2025, midnight
Bidirectional Mendelian randomization and cross-sectional study reveal depression as a causal risk factor for endometriosis.

Endometriosis (EMs) and depression are both common conditions that have a significant negative impact on quality of life. However, it is still unclear about the relationship between them. The study …

Published: Nov. 21, 2025, midnight
Serum miRNA-based diagnostic models for endometriosis: from discovery to validation.

Can a serum miRNA signature serve as a potential diagnostic biomarker for endometriosis (END)?

Published: Nov. 21, 2025, midnight
MiRNome alterations drive the malignant transformation of endometriosis into endometriosis-correlated ovarian cancer.

Endometriosis (EMS) is a chronic gynecological condition affecting 6-10% of reproductive-age women. These lesions, albeit of benign nature, present cancer-like features, and may progress to epithelial ovarian cancer (EOC) through …

Published: Nov. 21, 2025, midnight
The Effects of Emotional Freedom Technique on Pelvic Pain and Quality of Life in Women Diagnosed with Endometriosis: A Randomized Controlled Trial.

Objective: The primary goal of treatment for endometriosis (EMS), where pelvic pain is the most significant symptom, is the symptom alleviation. Medical treatment is typically employed until menopause or until …

Published: Nov. 21, 2025, midnight
Long-term risk of psychiatric disorders in women with endometriosis: A retrospective cohort study.

Endometriosis is a chronic, estrogen-dependent condition associated with substantial physical and psychological burden. Although psychiatric comorbidities are frequently reported, large-scale real-world data remain limited.

Published: Nov. 21, 2025, midnight
Impact of Physical Rehabilitation on Endometriosis and Adenomyosis-Related Symptoms: A Systematic Review and Meta-Analysis.

Objectives: The aim of this study is to summarize recent evidence of the effectiveness of rehabilitation interventions in managing symptoms related to endometriosis and adenomyosis. Methods: The review protocol was …

Published: Nov. 21, 2025, midnight
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