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Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review).

Endometriosis is a complex, chronic inflammatory gynecological disorder with estrogen‑dependent characteristics that severely impairs the quality of life of women and potentially leads to infertility. However, its pathogenesis remains poorly …

Published: Dec. 5, 2025, midnight
UBE2S-mediated deubiquitination of GLUT1 via USP10 regulates glucose metabolic reprogramming and immune microenvironment to promote fibrosis in endometriosis.

Endometriosis (EM) is a chronic inflammatory disorder characterized by the growth of ectopic endometrial-like tissue and fibrosis. Metabolic reprogramming, particularly enhanced glycolysis, and immune microenvironment dysregulation are key features of …

Published: Dec. 5, 2025, midnight
Genetic and Epigenetic Components in the Pathogenesis of Adenomyosis and Endometriosis in Adolescents.

Background: Adenomyosis and endometriosis are complex, estrogen-dependent gynecological conditions increasingly diagnosed in adolescents. While traditionally considered diseases of reproductive-age women, emerging evidence suggests a possible developmental origin in some cases, …

Published: Dec. 5, 2025, midnight
Spinal-Cord Stimulation for Intractable, Visceral Pain Associated With Endometriosis: Positive Results of a Feasibility Study.

Endometriosis, an estrogen-dependent chronic inflammatory disease, can cause visceral pain. Owing to its chronic nature, treatment can be challenging and insufficient in reducing all symptoms despite adequate management. Spinal-cord stimulation …

Published: Dec. 3, 2025, midnight
Natural bioactive compounds and herbal medicines targeting common signaling pathways in endometriosis: mechanisms and therapeutic implications.

For a very long time, herbal treatments have served as remedies for various humans and animals. Natural compounds typically have multiple pharmacological actions because they interact with various biological targets. …

Published: Dec. 2, 2025, midnight
The role of pharmacotherapy in the treatment of endometriosis: an update.

Endometriosis is a chronic inflammatory condition affecting ~10% of reproductive-age individuals and contributing significantly to infertility, pain, and reduced quality of life. Since our 2020 review, new pharmacologic strategies, updated …

Published: Dec. 2, 2025, midnight
Histomorphometric characterization of the endometrium in mules (Equus mulus): An approach to endometritis/endometrosis.

Mules (Equus mulus), as sterile hybrids between mares and donkeys, present a unique uterine morphology and physiology that remains poorly characterized. This study provides the first histomorphometric evaluation and transcriptional …

Published: Dec. 2, 2025, midnight
Xiao-Liu Tang (XLT), a traditional Chinese medicine formula that suppresses the progression of cervical cancer by inducing apoptosis and inhibiting cell migration.

Xiao-Liu Tang (XLT), a formulation grounded in the Traditional Chinese medicine (TCM) theory of Qi-Blood, has shown promise in alleviating endometriosis-related symptoms through clinical observations, with emerging evidence supporting its …

Published: Dec. 2, 2025, midnight
Exploring the impact of dietary theobromine on endometriosis risk: Evidence from Mendelian randomization and NHANES data.

Endometriosis is a chronic inflammatory estrogen-dependent inflammatory disorder. Theobromine has been implicated in diverse health benefits, including anti-inflammatory and vasodilatory properties. However, the precise association between theobromine and endometriosis remains …

Published: Nov. 28, 2025, midnight
Integrating inflammatory biomarkers and demographic variables with machine learning to predict endometriosis risk - Nature

Integrating inflammatory biomarkers and demographic variables with machine learning to predict endometriosis risk Nature

Published: Nov. 27, 2025, 5:43 p.m.
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