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Appendiceal inversion secondary to endometriosis and dilated mucinous adenoma identified on screening colonoscopy.

Appendix intussusception (AI), with ~200 reported cases, is a rare condition in which the appendix invaginates into the cecum [1]. Etiologies include benign and malignant pathologies including both intraluminal and …

Published: April 23, 2026, midnight
Single-Cell Transcriptomic Profiling and Machine Learning Integration Unveil Stromal Cell Heterogeneity in Endometriosis.

Endometriosis (EMs) affects approximately 10% of reproductive-age women worldwide, yet its pathogenesis remains incompletely understood. Abnormal cell differentiation and somatic mutations in the ectopic endometrial microenvironment play critical roles in …

Published: April 23, 2026, midnight
Peritoneal inclusion cyst following total laparoscopic hysterectomy and bilateral salpingo-oophorectomy in a transgender man.

Peritoneal inclusion cysts (PICs) are benign cystic lesions typically observed in women of reproductive age with prior pelvic surgery, endometriosis, or pelvic inflammatory disease. To date, no cases of PICs …

Published: April 23, 2026, midnight
Spontaneous Heterotopic Pregnancy and Its Clinical Implications.

Heterotopic pregnancy is a rare but potentially life-threatening gynecologic emergency and is particularly uncommon in natural conceptions. Heterotopic pregnancies are prone to misdiagnosis due to the atypical clinical manifestations, especially …

Published: April 23, 2026, midnight
Reproductive Pathways Across the Lifespan and Their Mental Health Impacts.

Reproductive health unfolds across the lifespan, and individuals may move through diverse pathways - including infertility, chronic gynecologic conditions such as endometriosis, pregnancy complications, assisted reproduction or gestational carriage. These …

Published: April 22, 2026, midnight
Editorial Note: Cohort profile: The Endometriosis pain QUality aftEr Surgical Treatment (EndoQUEST) Study.

Published: April 22, 2026, midnight
Individualized fertility preservation counselling for women with endometriosis-a systematic review.

Endometriosis is a chronic disease that may require surgical intervention under certain circumstances. Although the condition itself is associated with impaired fertility in 30-50% of affected individuals, surgical treatment may …

Published: April 22, 2026, midnight
Continuous estetrol/drospirenone regimen for the treatment of endometriosis-related pain: preliminary results.

Endometriosis is a chronic inflammatory condition that causes significant physical and psychological distress. This study aimed to evaluate the therapeutic efficacy and safety of a combined oral contraceptive containing estetrol …

Published: April 22, 2026, midnight
Cell-free regenerative therapies for female infertility: The emerging role of mesenchymal stem cell secretome.

Female reproductive disorders are a leading cause of infertility, affecting millions of women worldwide and resulting in significant emotional and social challenges. Despite advances in medical science, current treatment options …

Published: April 22, 2026, midnight
Dysregulated endometrial podocalyxin and LIF expression in women with ovarian endometrioma.

To investigate whether ovarian endometrioma is associated with disruption of the endocrine-regulated transition between the anti-adhesive modulator podocalyxin (PCX) and the adhesive modulator leukemia inhibitory factor (LIF) in the endometrium.

Published: April 21, 2026, midnight
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