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Follicular fluid cytokine and homocysteine profiles in poor ovarian responders with and without sonographic endometrioma: A comparative study.

To compare follicular fluid (FF) cytokine and homocysteine profiles in women with poor ovarian response (POR) undergoing in vitro fertilization (IVF), with and without sonographic endometrioma, and to explore potential …

Published: June 6, 2026, midnight
Anti-NRP1 peptide-engineered ROS/pH dual-responsive nanoparticles for Alpelisib delivery regulate Sema3A-NRP1/PI3K-AKT signaling to balance oxidative stress and inhibit angiogenesis in endometriosis.

Endometriosis progression is driven by oxidative stress and excessive angiogenesis within an inflammatory microenvironment. To overcome these challenges, we designed ROS/pH dual-responsive Alpelisib-loaded nanoparticles (Alp@TAT-AT7-NPs) functionalized with an anti-NRP1 peptide …

Published: June 6, 2026, midnight
Enhanced detection of vascularization in rectal endometriosis: A comparative study of microvascular flow and power Doppler.

Conventionally, rectal endometriotic nodules have been considered as poorly vascularized. However, new, more sensitive, Doppler techniques have been developed recently for assessing microvascularization. These new techniques might allow microvascularity in …

Published: June 5, 2026, midnight
HEXACHLOROBENZENE AND CHLORPYRIFOS, ENVIRONMENTAL POLLUTANTS THAT DISRUPT THE ENDOCRINE SYSTEM, PROMOTE ANGIOGENESIS ASSOCIATED WITH ENDOMETRIOSIS.

Endometriosis defined by the growth of endometrial tissues outside the uterus, affects women of reproductive age. A critical process in endometriosis progression, angiogenesis involves endothelial cell migration, proliferation and tube …

Published: June 5, 2026, midnight
Gut microbiota dysbiosis in endometriosis: mechanistic insights and gut microbiota-targeted therapeutic strategies.

Endometriosis (EMs) is a prevalent, estrogen-dependent gynecological disorder characterized by the ectopic implantation and proliferation of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of reproductive-aged women globally. Despite …

Published: June 5, 2026, midnight
Comparative post-marketing reporting signals of elagolix and myfembree in endometriosis: a FAERS pharmacovigilance study.

Elagolix and Myfembree are gonadotropin-releasing hormone (GnRH)-pathway therapies used for endometriosis, but their post-marketing safety reporting patterns remain incompletely characterized. Because spontaneous reporting databases are susceptible to reporting bias and …

Published: June 5, 2026, midnight
SGLT2 Inhibition as a Novel Therapeutic Strategy in Rheumatic Heart Disease.

Rheumatic heart disease (RHD) remains a major cause of cardiovascular morbidity and premature mortality among children and young adults, particularly in low- and middle-income countries. Current management relies on antibiotic …

Published: June 4, 2026, midnight
Initial Results of FAPI PET/MRI to Assess the Extent of Endometriosis.

Endometriosis is a common gynecologic disorder often associated with chronic pelvic pain, infertility, and reduced quality of life. Conventional imaging modalities, such as transvaginal ultrasound and MRI, may underestimate the …

Published: June 4, 2026, midnight
A woman's worth: Self-compassion as a mediator between optimism and beliefs about motherhood, identity, and infertility of women with endometriosis.

The aim of the present study was to analyze the mediating role of self-compassion between trait optimism and beliefs about woman identity, motherhood and infertility among women with endometriosis, adjusting …

Published: June 4, 2026, midnight
Emerging signal transduction pathways and the role of bacterial extracellular vesicles linked to the pathogenesis of endometriosis.

Endometriosis is defined as the ectopic proliferation of endometrial cells. Aberrant signal transduction is present in ectopic endometriotic lesions, and bacteria also contributes to the development of endometriosis by transmitting …

Published: June 4, 2026, midnight
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