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Cancer Risk Profile of the Levonorgestrel-Releasing Intrauterine Device: A Narrative Review.

Background/Objectives: The levonorgestrel-releasing intrauterine device (LNG-IUD) is widely used as a long-acting reversible contraceptive and as a therapeutic option for heavy menstrual bleeding, endometriosis, adenomyosis, and endometrial hyperplasia. Although its …

Published: July 23, 2026, midnight
Reply to "Reassessing the Proposed Creatine-PrP Axis in Endometriosis: Methodological and Mechanistic Considerations".

This Correspondence is a formal response to the Comment by Dr. Machado regarding our publication "Creatine Promotes Endometriosis by Inducing Ferroptosis Resistance via Suppression of PrP." We address several conceptual …

Published: July 20, 2026, midnight
[Endometriosis pain research in Germany : ENDO-PAIN and StEPP-UPP-two new research consortia on endometriosis pain].

Endometriosis is one of the most common causes of chronic pelvic or lower-abdominal pain, yet mechanisms, predictors, and patient-centered treatment pathways remain insufficiently defined. This article summarizes the situation in …

Published: July 20, 2026, midnight
Mendelian randomization of risk factors for premenstrual disorders.

The causal role of established risk factors for premenstrual disorders (PMDs) remains unclear. We used Mendelian randomization (MR) to assess causality for eight known-risk factors identified through a literature review. …

Published: July 16, 2026, midnight
N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence.

Endometriosis is a chronic inflammatory and estrogen-dependent disease in which oxidative stress, immune dysregulation, and lesion-supportive microenvironmental signaling contribute to lesion development. N-acetylcysteine (NAC), a glutathione-replenishing and redox-modulating agent, has …

Published: July 16, 2026, midnight
The genetics of primary dysmenorrhea: a systematic review.

Dysmenorrhea is the most common gynaecological condition in women of reproductive age. Approximately 90% of cases are primary dysmenorrhea (PDM) which is not associated with underlying pathology. Dysmenorrhea can have …

Published: July 15, 2026, midnight
Endometriosis and postdigital health practices.

This paper aims to analyse selected online narratives of women with endometriosis who leverage the affordances of these platforms to share their lived experiences. Through discourse analysis, this study critically …

Published: July 15, 2026, midnight
The role of tumor necrosis factor alpha in regulating CYFRA 21-1 as a potential biomarker for endometriosis: A cross-sectional study.

Background: Endometriosis is one of the most common gynecological conditions, and the gold standard for its diagnosis is laparoscopy. Cytokeratin fragment 21-1 (CYFRA 21-1) has emerged as a potential biomarker …

Published: July 14, 2026, midnight
Mimicry in the Colon: Endometriosis-Associated Carcinoma in a Post-hysterectomy Patient.

Endometriosis is a benign yet chronic gynecologic condition that, in rare cases, may undergo malignant transformation. Although endometriosis-associated malignancies most commonly arise in the ovary, extragonadal sites may also be …

Published: July 12, 2026, midnight
Comprehensive transcript and protein profiling reveals ERα rather than ERβ as the predominant estrogen receptor in human endometriotic lesions.

Endometriosis (EMS) is a chronic estrogen-dependent inflammatory disease. Although several studies have suggested a key role for estrogen receptor ERβ in EMS lesion development, its detection has been challenged by …

Published: July 11, 2026, midnight
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