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Is exercise duration more important than intensity in endometriosis?

Exercise may be a useful adjunct treatment strategy to manage symptom severity and improve quality of life of women with endometriosis. This cross-sectional observational study aimed to investigate the associations …

Published: Dec. 30, 2025, midnight
Association Between Remnant Cholesterol and Endometriosis Findings from NHANES 1999-2006.

Endometriosis is a chronic gynecological disorder causing significant morbidity and health burden. Recent evidence suggests that lipid metabolism, particularly remnant cholesterol (RC), may be involved in its development. RC-the cholesterol …

Published: Dec. 30, 2025, midnight
Expanding the spectrum of AFF2 undifferentiated sarcoma associated to endometriosis: a novel ZDHHC9::AFF2 fusion sarcoma with high-grade features and poor prognosis.

The AFF2 gene encodes a protein involved in transcriptional regulation and chromatin remodeling. While primarily associated with Fragile X syndrome, AFF2 fusions have recently been identified in certain malignancies, mostly …

Published: Dec. 28, 2025, midnight
Appendiceal endosalpingiosis: a rare case with potential implications for gynecological malignancy.

Appendiceal endosalpingiosis is an exceedingly rare histopathologic finding with uncertain clinical significance and unknown implications for management. Most often, endosalpingiosis occurs within ovary, fallopian tube, omentum, and uterus. Previous literature …

Published: Dec. 28, 2025, midnight
MicroRNA Crossroads in PCOS and Endometriosis.

In the intricate landscape of health disorders in women, polycystic ovary syndrome and endometriosis stand out. Despite their complete etiology being unknown, their impact on women's health and link to …

Published: Dec. 23, 2025, midnight
Endometriosis Then and Now: A 100-Year Journey Around Pathogenesis and Clinicopathologic Associations.

Nearly a century has passed since a seminal review article was published in 1928 in Archives of Pathology on ectopic endometriosis, presenting the dominant pathogenetic theories of the era: the …

Published: Dec. 22, 2025, midnight
Systematic analyses uncover endocrine-disrupting chemical-responsive genes linked to endometriosis.

Endometriosis is a chronic, estrogen-dependent disorder influenced by both genetic and environmental factors, including endocrine-disrupting chemicals (EDCs). This study aimed to identify EDC-responsive genes contributing to endometriosis risk by integrating …

Published: Dec. 22, 2025, midnight
APOL1-mediated kidney disease: a narrative review of the lessons learnt from the past 15 years.

Fifteen years have elapsed since the publication of the seminal work establishing the association between risk variants in the Apolipoprotein L1 (APOL1) gene and kidney disease in individuals of African …

Published: Dec. 17, 2025, midnight
Endometriosis phenotypes and staging in relation to lipid biomarkers: Findings from the ENDO Cohort Study.

Endometriosis has been linked to cardiometabolic alterations, but whether these associations vary by disease severity or phenotype is unclear. We examined lipid profiles across endometriosis diagnosis, stage, and typology.

Published: Dec. 15, 2025, midnight
From Gynecological Endocrine Disorders to Cardiovascular Risk: Insights from Rat Models.

Gynecological endocrine disorders, including polycystic ovary syndrome (PCOS), endometriosis as well as primary ovarian insufficiency (POI)/premature ovarian failure (POF), significantly impact women's reproductive health and overall well-being. While these conditions …

Published: Dec. 13, 2025, midnight
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