Latest Articles

The role of anti-Müllerian hormone as a therapeutic agent to preserve the ovarian follicle pool during chemotherapy.

Cancer treatments can deplete the ovarian follicle reserve, causing infertility and early menopause, with subsequent decline in cardiovascular, cognitive, and overall women's health. Medical measures to prevent this chemotherapy-induced ovarian …

The role of omentin-1 in female reproduction: a critical review.

White adipose tissue is now recognized as an active endocrine organ that secretes numerous bioactive molecules known as adipokines. These proteins regulate essential physiological processes, including energy metabolism, inflammation, and …

Comparative analysis of natural versus ovarian stimulation cycles in intrauterine insemination by diverse infertility indications.

To describe clinical intrauterine insemination (IUI) outcomes among infertile patients with different infertility indications, and further compare reproductive outcomes between natural cycle (NC) and ovarian stimulation cycle (OSC) IUI.

Research progress of ferroptosis in gynecological diseases.

The concept of ferroptosis debuted as a newly defined programmed cell death in 2012. Among programmed cell death mechanisms, ferroptosis stands out as being fundamentally dependent on iron. At the …

Patient-derived eutopic and ectopic endometrial stromal cells: characterization and development of immortalized lines.

Ovarian endometriosis is an estrogen-dependent inflammatory disorder in which endometrial stromal cells are key cellular contributors to hormone-immune crosstalk and lesion persistence. Here, we isolated paired eutopic (NESC) and ectopic …

Diagnosis-dependent metabolic reprogramming of follicular fluid.

The follicular fluid (FF) microenvironment plays a critical role in oocyte maturation and embryo development, reflecting local ovarian activity and systemic metabolic status. While metabolic alterations in FF have been …

Appendiceal endometriosis mimicking acute appendicitis in a young woman: A case report.

Appendiceal endometriosis is a rare form of extragenital endometriosis that can mimic acute appendicitis. This reports presents the case of a 19-year-old woman with no significant medical history who presented …

Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics.

Lactate is increasingly recognized not only as a metabolic end product of glycolysis but also as a signaling metabolite that links metabolic reprogramming to epigenetic and transcriptional regulation through protein …

Regarding "Risk, prevalence and survival outcomes of ovarian cancer in women with endometriosis: the ENDOCANCER systematic review and meta-analysis".

Malignant transformation of uterine serosal endometriosis to clear cell carcinoma in a postmenopausal patient: a rare case report.

Endometriosis is a prevalent benign condition among women of reproductive age. While the overall rate of endometriosis-associated malignancy is low, the risk of malignant transformation increases significantly in postmenopausal patients, …