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Aberrant mitochondria in endometriosis: From pathogenic mechanisms to therapeutic opportunities.

Endometriosis affects about 10% of women of reproductive age and is a major cause of chronic pelvic pain and infertility, yet current therapies often fail to provide lasting relief. Mitochondrial …

Published: June 2, 2026, midnight
Epigenetics, Oxidative Stress, and the Microbiome in Endometriosis: Toward an Integrated Mechanistic Framework for Precision Medicine.

Endometriosis (EM) is a chronic, estrogen-dependent inflammatory disorder affecting approximately 6-10% of women of reproductive age in the general population and remains a major cause of chronic pelvic pain and …

Published: June 1, 2026, midnight
Contributions of T-helper 9 cells in endometriosis-associated inflammation and lesion growth.

Endometriosis is an inflammatory gynecologic disease characterized by ectopic growth of endometrial-like tissue, resulting in pelvic pain and infertility. T-helper 9 (Th9) cells play a known role in various chronic …

Published: May 30, 2026, midnight
Central sensitization in patients with chronic pelvic pain resistant to hormonal therapy: A cross-sectional study of prevalence and clinical correlates in a tertiary referral cohort.

Chronic pelvic pain (CPP) affects over 25% of women, with endometriosis being a predominant cause. Central sensitization, particularly pelvic and perineal pain central sensitization (PPCS), is increasingly recognized as a …

Published: May 28, 2026, midnight
Real-World Implementation of EndoConnect in Brazilian Primary Care: Formative Study of Usability, Engagement, and Equity in Digital Endometriosis Care.

Endometriosis is a chronic gynecological condition affecting approximately 10% of women of reproductive age worldwide and is associated with chronic pelvic pain, infertility, and reduced quality of life. In Brazil's …

Published: May 27, 2026, midnight
Gastrointestinal Tract Endometriosis: Clinicopathologic Features and Anatomic Distribution in an Institutional Cohort.

Endometriosis is defined by the presence of endometrial glands and stroma outside the uterine cavity. Although it typically presents within the pelvis, extragenital manifestations are well documented with gastrointestinal (GI) …

Published: May 27, 2026, midnight
HEALTH Yeah! Episode 32: Heavy Bleeding and Pelvic Pain – Rethinking “Normal” - Stony Brook Medicine

HEALTH Yeah! Episode 32: Heavy Bleeding and Pelvic Pain – Rethinking “Normal” Stony Brook Medicine

Published: May 26, 2026, 3:13 p.m.
The Impact of Endometriosis on Ovarian Reserve: A Systematic Review.

Endometriosis is a chronic inflammatory condition, causing severe pelvic pain, organ dysfunction, infertility, and mental health issues. Ovarian reserve, indicating the quantity and quality of a woman's oocytes, is negatively …

Published: May 26, 2026, midnight
O-GlcNAc modification regulates autophagy and apoptosis in endometriosis.

Endometriosis is a common, chronic gynecological disorder characterized by the presence of endometrial-like tissue outside the uterine cavity, frequently associated with significant morbidities such as pelvic pain and infertility. Elucidating …

Published: May 25, 2026, midnight
Circulating Transfer RNA Related Fragment Abundance After Experimental Endometriosis Induction in Baboons.

Endometriosis is a chronic systemic disease affecting approximately 10-15% of women of reproductive age, often resulting in chronic pelvic pain and infertility. Despite its high prevalence, diagnosis is frequently delayed. …

Published: May 23, 2026, midnight
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