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Exploring the value of a well-established conditioned pain modulation paradigm in women: a Translational Research in Pelvic Pain (TRiPP) study.

Conditioned pain modulation (CPM) is considered a human proxy for descending inhibitory pain pathways. However, there is wide variation in the CPM response described in the literature and ongoing debate …

Published: March 12, 2025, midnight
Enriching tuberculosis research by measuring poverty better: a perspective.

The relationship between poverty and tuberculosis (TB) is well-documented, as socio-economic deprivation constitutes a risk factor that drives TB transmission and progression while hindering treatment adherence. Despite the importance of …

Published: Feb. 21, 2025, midnight
A Fibronectin (FN)-Silk 3D Cell Culture Model as a Screening Tool for Repurposed Antifibrotic Drug Candidates for Endometriosis.

This study advances sustainable pharmaceutical research for endometriosis by developing in vitro 3D cell culture models of endometriotic pathophysiology that allow antifibrotic drug candidates to be tested. Fibrosis is a …

Published: Feb. 19, 2025, midnight
Single-cell dual-omics reveals translational and transcriptional landscapes and regulations in oocytes from ovarian endometriosis patients.

A significant proportion of women in their reproductive years are afflicted by endometriosis. And one of the major contributing factors to infertility linked to ovarian endometriosis is thought to be …

Published: Feb. 17, 2025, midnight
Pelvic pain & endometriosis: the development of a patient-centred e-health resource for those affected by endometriosis-associated dyspareunia.

We recognized a paucity of accessible, evidence-based, empowering patient-centred resources for those with endometriosis-associated dyspareunia. Affecting more than 50% of people with endometriosis, dyspareunia can significantly impact relationships, chronic pain …

Published: Feb. 13, 2025, midnight
Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.

Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical …

Published: Feb. 6, 2025, midnight
Transforming the #Enzian classification into a four-stage system: A feasibility study by comparison with the 2021 AAGL endometriosis classification.

To develop a translation model of the #Enzian classification into a 4-stage system and to evaluate its performance in a retrospective endometriosis cohort.

Published: Feb. 5, 2025, midnight
Novel screening approach for stem cell selective inhibitors and their possible translational therapeutic potential for endometriosis.

Endometriosis is an estrogen-dependent benign disease characterized by growth of the endometrial tissue outside the uterine wall. Several reports suggest the possibility of the pathogenesis and recurrence of endometriosis being …

Published: Jan. 11, 2025, midnight
Engineering nanosystems for regulating reproductive health in women.

Reproductive health-related diseases have a significant impact on the well-being of millions of women worldwide, severely compromising their quality of life. Women encounter unique challenges in terms of reproductive health, …

Published: Jan. 1, 2025, midnight
Chinese translation, cross-cultural adaptation, and psychometric validation of patient-reported outcome measurement- questionnaire about gynecological and pelvic pain symptoms (ENDOPAIN-4D).

The aim of this study was to cross-culturally translate a questionnaire about gynecological and pelvic pain symptoms (ENDOPAIN-4D) patient-reported outcome measurement (PROM) into Chinese and evaluate its reliability and validity.

Published: Dec. 21, 2024, midnight
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