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Adenomyosis, Infertility and Maternal-Fetal Outcomes: Diagnostic and Therapeutic Strategies Across Disease Phenotype-A Narrative Review.

Adenomyosis is a chronic estrogen-dependent disorder that may adversely affect reproductive health. Increasing evidence suggests that its reproductive and obstetric consequences may vary according to disease phenotype, including focal versus …

Published: Aug. 29, 2026, midnight
Revisiting the role of danazol in the contemporary management of endometriosis-related pain: a systematic review.

Danazol is a synthetic steroid approved in 1976 for the treatment of endometriosis-associated pain. Despite its established efficacy, its clinical use has markedly declined due to androgenic and metabolic adverse …

Published: Aug. 28, 2026, midnight
Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care.

Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances …

Published: Aug. 28, 2026, midnight
Altered Progesterone Receptor Isoform Expression in Endometrial Cells: A Preliminary Immunohistochemical Study in Endometriosis.

Background/Objectives: The objective of this exploratory study was to test the hypothesis that endometriosis is associated with altered abundance and cellular location of nuclear progesterone receptor (PR) isoforms in eutopic …

Published: Aug. 28, 2026, midnight
From polygenic risk to functional genomics: a framework for precision gynecological disease modeling.

Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a framework integrating …

Published: Aug. 27, 2026, midnight
Shaofu Zhuyu decoction can inhibit the progression of endometriosis fibrosis through the transforming growth factor-β1/ smads signaling pathway mediated by 5' adenosine monophosphate-activated protein kinase.

To investigate the mechanisms by which Shaofu Zhuyu decoction (SFZYD, ) modulates fibrosis in a mouse model of endometriosis.

Published: Aug. 26, 2026, midnight
Single-stapled versus double-stapled colorectal anastomosis after anterior resection: Systematic review and meta-analysis of short-term and functional outcomes.

The double-stapled anastomosis technique is widely considered the standard approach for colorectal anastomosis after anterior rectal resection. Recently, the single-stapled anastomosis technique has gained attention because it may reduce potential …

Published: Aug. 26, 2026, midnight
Transcriptome differences in lesions by color, and cancer mutations in endometriosis.

Endometriosis is a disease where cells similar to those of the uterine lining grow outside of the uterus, embedding into tissues and organs in the abdominal cavity, forming lesions and …

Published: Aug. 25, 2026, midnight
The role of SYNE1/2 variants as a potential predisposition factor for the onset of endometriosis.

Endometriosis (EM) is a chronic, inflammatory gynaecological disorder defined by the presence of endometrial-like tissue outside the uterine cavity, most frequently affecting the ovaries, peritoneum, and uterosacral ligaments. Despite its …

Published: Aug. 25, 2026, midnight
Precise Surgical Navigation of Endometriosis via NIR-II Fluorescence Imaging With a Semiconducting Polymeric Probe.

Endometriosis is a prevalent gynecological disorder characterized by ectopic growth of endometrial-like tissue, often causing chronic pain, infertility, and systemic inflammation. Accurate detection and complete surgical resection remain challenging because …

Published: Aug. 24, 2026, midnight
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