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Mechanisms of Endometrioma-Mediated Ovarian Damage: Myths and Facts.

Ovarian endometriomas (OEMs), cystic formations within the ovaries, are a significant manifestation of endometriosis and present in 20-40% of affected women. Despite extensive research, the pathogenesis of endometriosis remains unclear, …

Published: March 21, 2025, midnight
Analysis of the Biopsychosocial Impacts Associated with Endometriosis to Improve Patient Care.

Endometriosis is a non-malignant, inflammatory condition that impacts individuals across various hormonal stages, including before their first menstruation, throughout their reproductive years, and after menopause. This condition arises when tissue …

Published: March 21, 2025, midnight
Chronic Pelvic Pain in Women: Evaluation and Treatment.

Chronic pelvic pain affects up to 26% of individuals with female anatomy and is defined as at least 6 months of pain that is perceived to originate in the pelvis. …

Published: March 20, 2025, midnight
Utilising Human Myometrial and Uterine Fibroid Stem Cell-Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids.

Uterine fibroids (UFs) are the most common benign gynecologic tumours affecting women of reproductive age. This study aims to deepen the understanding of UFs complex aetiology through harnessing the power …

Published: March 20, 2025, midnight
SCM-198 Inhibits EMS Development by Reversing Decreased Proportions of IFN-γ+T Cells and CCR5+T Cells.

Endometriosis is a common gynecological disease that causes severe pain and infertility. However, the available treatments for EMS are limited. SCM-198, a synthetic form of leonurine, possesses various abilities, including …

Published: March 20, 2025, midnight
Glypican3 and serglycin as potential biomarkers involved in the pathogenesis of ovarian endometriosis.

Endometriosis, a non-malignant gynecological disorder characterized by debilitating symptoms, displays several cancer-like characteristics, including metastatic behavior and extracellular matrix (ECM) remodeling. The dynamics of ECM are largely influenced by proteoglycans …

Published: March 20, 2025, midnight
Analysis of risk factors for recurrence after laparoscopic myomectomy: A retrospective study.

At present, there is unclear on the risk factors of recurrence after myomectomy. In this study, we hope to provide reference for the choice of treatment for patients with uterine …

Published: March 19, 2025, 12:17 a.m.
Development of the COMPASS model of endometriosis: A COmprehensive model of pain encompassing agency, systemic factors and sense making.

Endometriosis is a chronic and progressive condition commonly associated with debilitating pain. Treatments for endometriosis pain are limited and usually invasive. Psychological interventions are a non-invasive intervention option and have …

Published: March 19, 2025, 12:13 a.m.
Assessing healthcare needs in endometriosis: a scoping review.

Women with endometriosis still have to seek the legitimacy of their disease from the medical community and often feel unheard. This scoping review aims to map the scientific literature to …

Published: March 19, 2025, midnight
Unveiling Potential Blood Markers for Endometriosis Through the Integration and Experimental Validation of Immune Cell Traits Genome and Genome-Wide Associated Data.

While endometriosis (EM) has been previously associated with multiple immune factors, the causal relationship underlying these associations remains unclear.

Published: March 19, 2025, midnight
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