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GSK’s Jemperli now standard in endometrial cancer as reimbursement expands to 1st-line therapy - koreabiomed.com

GSK’s Jemperli now standard in endometrial cancer as reimbursement expands to 1st-line therapy koreabiomed.com

Published: Dec. 1, 2025, 6:49 a.m.
ZMIZ1 and estrogen receptor α form an essential partnership in endometrial biology.

Estrogen receptor α (ESR1) is a pivotal regulator of endometrial homeostasis and reproductive function, yet the coregulators that fine tune its transcriptional activity remain incompletely defined. In this issue of …

Published: Dec. 1, 2025, midnight
Transcriptional coregulator ZMIZ1 modulates estrogen responses that are essential for healthy endometrial function.

Estrogen is a critical regulator of endometrial health. Aberrant estrogen stimulation can result in infertility, endometrial cancer, and endometriosis. Here, we identified Zinc Finger MIZ-Type Containing 1 (Zmiz1) as a …

Published: Dec. 1, 2025, midnight
From Mice to Primates: Assessing Hormone-Based Endometriosis Models for Preclinical and Therapeutic Insights.

Endometriosis, a complex gynecological disorder characterized by ectopic endometrial-like tissue, affects over 10% of women, causing chronic pain and infertility. Despite extensive research, its pathophysiology remains incompletely understood, with proposed …

Published: Dec. 1, 2025, midnight
Double Trouble: A Rare Clinical Presentation of Bladder and Umbilical Endometriosis.

Endometriosis is a common condition among women where tissue resembling the uterine lining grows outside the uterus. This misplaced tissue can develop in several areas, including the peritoneum, pouch of …

Published: Nov. 30, 2025, midnight
Dissecting endometrial cancer complexity in response to standard and targeted therapies - Nature

Dissecting endometrial cancer complexity in response to standard and targeted therapies Nature

Published: Nov. 28, 2025, 5:08 p.m.
Endometrial Stromal Cells from Endometriosis Patients Reflect Lesion-Type-Specific Heterogeneity.

Endometriosis, a disease affecting about one out of ten women, is characterized by the growth of endometrial-like tissue outside the uterine cavity. There is significant disease heterogeneity, but the pathophysiological …

Published: Nov. 28, 2025, midnight
Exploring the combined antiproliferative effects of artesunate and resveratrol in Ishikawa endometrial cancer cells - News-Medical

Exploring the combined antiproliferative effects of artesunate and resveratrol in Ishikawa endometrial cancer cells News-Medical

Published: Nov. 27, 2025, 10:29 a.m.
Impact of pelvic endometriosis on the chances of pregnancy in the context of oocyte donation.

Endometriosis is diagnosed in 25% to 40% of infertile patients. This disease can affect ovarian reserve and oocyte quality, as a result Assisted Reproductive Technology is often required. However, the …

Published: Nov. 27, 2025, midnight
DESTINY-Endometrial01 Will Examine T-DXd Plus Rilvegostomig or Pembrolizumab in HER2+ pMMR Endometrial Cancer - OncLive

DESTINY-Endometrial01 Will Examine T-DXd Plus Rilvegostomig or Pembrolizumab in HER2+ pMMR Endometrial Cancer OncLive

Published: Nov. 26, 2025, 7:03 p.m.
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