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Comparative post-marketing reporting signals of elagolix and myfembree in endometriosis: a FAERS pharmacovigilance study.

Elagolix and Myfembree are gonadotropin-releasing hormone (GnRH)-pathway therapies used for endometriosis, but their post-marketing safety reporting patterns remain incompletely characterized. Because spontaneous reporting databases are susceptible to reporting bias and …

Published: June 5, 2026, midnight
Mesonephric-like adenocarcinoma as an unexpected histological result after fertility saving procedure for presumed adenomyosis: a case report.

We report an unexpected case of mesonephric-like adenocarcinoma initially treated as a diffuse adenomyosis in a patient presenting with primary infertility. The aim of this report is to raise clinical …

Published: June 5, 2026, midnight
SGLT2 Inhibition as a Novel Therapeutic Strategy in Rheumatic Heart Disease.

Rheumatic heart disease (RHD) remains a major cause of cardiovascular morbidity and premature mortality among children and young adults, particularly in low- and middle-income countries. Current management relies on antibiotic …

Published: June 4, 2026, midnight
Initial Results of FAPI PET/MRI to Assess the Extent of Endometriosis.

Endometriosis is a common gynecologic disorder often associated with chronic pelvic pain, infertility, and reduced quality of life. Conventional imaging modalities, such as transvaginal ultrasound and MRI, may underestimate the …

Published: June 4, 2026, midnight
Emerging signal transduction pathways and the role of bacterial extracellular vesicles linked to the pathogenesis of endometriosis.

Endometriosis is defined as the ectopic proliferation of endometrial cells. Aberrant signal transduction is present in ectopic endometriotic lesions, and bacteria also contributes to the development of endometriosis by transmitting …

Published: June 4, 2026, midnight
Gut-reproduction axis: genome-wide pleiotropic and prospective evidence linking inflammatory bowel disease with gynecological disorders.

We aimed to explore shared genetic architectures and potential causal associations between inflammatory bowel disease (IBD) and gynecological diseases, including ovarian cysts (OC), pelvic inflammatory disease (PID), and endometriosis (EMs), …

Published: June 4, 2026, midnight
Psychological flexibility and pain catastrophizing in endometriosis: Incremental validity and interaction effects in predicting psychosocial outcomes.

Psychological distress and reduced health-related quality of life are common among women with endometriosis, particularly when the condition is accompanied by chronic pain. Psychological flexibility (PF), a core process in …

Published: June 4, 2026, midnight
TICAM1-Mediated TLR3/TLR4 Signaling Promotes Endometrial Stromal Cell Proliferation, Migration, and Invasion in Endometriosis via IRF3/IFN-β Axis.

Endometriosis (EMs) is an estrogen-dependent inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity, yet its precise pathogenesis remains incompletely elucidated. TICAM1, a key adaptor protein …

Published: June 4, 2026, midnight
Hypoxia-induced regulations of cell adhesion molecules and their implications for pathogenesis, diagnosis, and treatment of endometriosis.

Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity, affecting up to 10% of women of reproductive age. Despite extensive research, its …

Published: June 4, 2026, midnight
Pelvic neurovascular anatomy and avascular spaces: a pictorial essay of key surgical landmarks.

A precise understanding of pelvic neurovascular anatomy is essential for minimizing complications during advanced gynecological and pelvic surgery. Retroperitoneal dissection requires a clear appreciation of spatial relationships between vascular, neural, …

Published: June 3, 2026, midnight
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