Latest Articles

Functional outcomes after laparoscopic colorectal resection with natural orifice specimen extraction and conventional specimen extraction for deep endometriosis: a 24-month prospective cohort study.

To assess changes in bowel function, pain symptoms, and endometriosis-related quality of life over 24 months after laparoscopic colorectal resection with natural orifice specimen extraction (NOSE) and conventional abdominal specimen …

Integrative analysis and experiment validation of SLC12A8 as a biomarker for the malignant transition from endometriosis to endometriosis associated ovarian cancer.

Endometriosis (EM) is a chronic inflammatory, estrogen‑dependent benign gynecological disorder. A subset of patients with EM may subsequently develop endometriosis‑associated ovarian cancer (EAOC), implying a biological continuum between these two …

The Endocannabinoid System in Endometriosis-Associated Pain: Mechanisms, Molecular Targets, and Therapeutic Implications.

Endometriosis is a chronic gynecological disorder affecting approximately 10% of reproductive-age women, characterized by the ectopic growth of endometrial tissue and severe pain, including dysmenorrhea, chronic pelvic pain, dyspareunia, dysuria, …

Transperineal Ultrasound in Chronic Pelvic Pain: A Systematic Review.

This systematic review aimed to explore the application and effectiveness of transperineal ultrasound as a diagnostic tool for evaluating pelvic floor musculature (PFM) dysfunction in patients with chronic pelvic pain …

Correction: Collagen-binding ⁶⁸Ga-CBP8 PET/MR in Deep Pelvic Endometriosis: First-in-human Application.

NRF2 Signalling in Endometriosis: A Hormone-Independent Axis for Fertility-Preserving Therapeutic Innovation.

Endometriosis is a chronic inflammatory disease characterised by pain, infertility and recurrence. Current pharmacological management relies largely on hormonal suppression, which can reduce pain and disease activity but does not …

Prevalence and Etiological Pattern of Infertility in Women Presenting to a Gynecology Clinic in a Secondary Health Facility, South-South, Nigeria: A Cross-Sectional Study.

Infertility is a major reproductive health problem with significant social, psychological, and economic consequences. In Nigeria, cultural expectations surrounding childbearing may intensify stigma and emotional distress, particularly among women. This …

The importance of power in photobiomodulation: a systematic review and meta-analysis of high-intensity laser therapy.

Low-level laser therapy (LLLT; ≤ 0.5 W) is guideline-recommended in the United States for shallow-tissue oral mucositis and other superficial pathologies but has generally failed in trials for deeper tissue …

Patient- and disease-related characteristics to anticipate segmental resection for isolated rectal endometriosis: a multicenter prospective study.

To identify predictors for segmental resection in patients with an isolated rectal endometriotic nodule (i.e. involvement of at least the muscular layer in depth and up to 15cm to the …

Compartment-specific inflammation-metabolism remodeling across eutopic and ectopic endometriosis tissues with cross-context evaluation in TCGA-UCEC.

Endometriosis exhibits tissue- and cell-compartment heterogeneity in inflammatory and metabolic activity. We evaluated compartment-specific remodeling in primary endometriosis tissues and used TCGA-UCEC as an independent cancer comparison.