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Reduced type 2 epithelial-mesenchymal transition serves as a risk factor for the progression from endometriosis to endometriosis-associated ovarian cancer.

Endometriosis-associated ovarian cancer (EAOC) is a rare subtype of ovarian cancer arising from the malignant transformation of endometriosis (EMS). Despite growing clinical awareness, its underlying pathogenic mechanisms are not fully …

Published: May 1, 2026, midnight
Transfer RNA-derived small RNAs in female reproductive disorders: emerging roles and clinical implications.

Female reproductive disorders present significant challenges worldwide. Transfer RNA-derived small RNAs (tsRNAs), a structurally diverse class of non-coding RNAs mainly comprising tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs), have emerged …

Published: April 29, 2026, midnight
Clear cell carcinoma developed on hepatic endometriosis: a case report and review of the literature.

Endometriosis is a chronic estrogen-dependent disorder that is generally localized in the pelvis affecting up to 10% of women in the reproductive age. Extra-pelvic locations are estimated to 9% of …

Published: April 29, 2026, midnight
Characterization of elevated levels of endometrial renin-angiotensin system components suggest a role in endometrial repair.

Each month, the endometrium is shed, regenerated, and transformed in response to changing hormone levels. These processes occur in a tightly regulated manner, and irregularities are linked with reproductive health …

Published: April 28, 2026, midnight
Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications.

Vitamin D a fat-soluble steroid hormone signals through Vitamin D Receptors (VDRs) located throughout the ovaries, uterus, placenta, hypothalamus, and pituitary gland, influencing immune regulation and female reproductive physiology. This …

Published: April 27, 2026, midnight
Stage-Related Changes in TGF-β Isoforms in PBMC Culture Supernatants in Endometriosis: A Prospective Case-Control Study.

Endometriosis is a chronic inflammatory disease in which transforming growth factor-beta (TGF-β) has been implicated in immune dysregulation, extracellular matrix remodeling, and fibrosis. Data on baseline secretion of TGF-β isoforms …

Published: April 27, 2026, midnight
Analysis of risk factors compromising embryo quality and quantity in patients with endometriosis.

This study aims to analyze the clinical factors affecting embryo quality and quantity in endometriosis patients undergoing in vitro fertilization/intracytoplasmic sperm injection and embryo transfer (IVF/ICSI-ET), thereby providing a reference …

Published: April 23, 2026, midnight
Polypoid endometrioma mimicking malignant transformation: a case report and systematic review.

To report a case of polypoid ovarian endometrioma mimicking malignant transformation, review the literature on this rare entity, and highlight its implications for surgical management and fertility preservation.

Published: April 22, 2026, midnight
Transdisciplinary Approach to Endometriosis-Related Chronic Pelvic Pain in Colombia: A Consensus Statement for Patient-Centered Care.

This consensus statement seeks to transform endometriosis care in Colombia by standardizing clinical management through the establishment of transdisciplinary teams and the use of quality indicators; strengthening education and awareness …

Published: April 17, 2026, midnight
Inflammasomes meet organoids and artificial intelligence: unraveling the complexity of gynecological inflammation.

Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues …

Published: April 17, 2026, midnight
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