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The letrozole use in reproductive medicine: Beyond aromatase inhibition - a comprehensive review.

Letrozole and other aromatase inhibitors are increasingly recognized as first-line ovulation induction (OI) medications, offering an efficient and physiologic approach to ovarian stimulation that enhances outcomes in reproductive medicine. By …

Published: Feb. 17, 2026, midnight
Central sensitization in women with endometriosis: a cross-sectional study.

Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form …

Published: Feb. 17, 2026, midnight
Mechanism of Bushen Wenyang Huayu Formula against oxidative damage by Let-7b-Bach1 in the treatment of endometriosis.

Endometriosis (EMs) is a prevalent and challenging gynecological disease and current therapeutic outcomes are suboptimal. Traditional Chinese medicine (TCM) has numerous advantages in treating EMs. Bushen Wenyang Huayu Formula (BWHF), …

Published: Feb. 17, 2026, midnight
A Dive into the Invisible: The Vaginal and Endometrial Microbiota in Gynecologic and Obstetric Disorders: A Narrative Review.

The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …

Published: Feb. 17, 2026, midnight
Indocyanine green in intestinal endometriosis surgery: a multicenter evaluation of anastomotic safety.

To evaluate whether the use of intraoperative indocyanine green (ICG) fluorescence impacts anastomotic safety and surgical outcomes in patients undergoing bowel endometriosis resection.

Published: Feb. 16, 2026, midnight
Reproductive outcomes after surgical correction of congenital obstructive genital tract anomalies: A systematic review and quantitative pooled analysis of published data.

Congenital obstructive genital tract anomalies are rare but clinically significant causes of menstrual outflow obstruction, endometriosis, and subfertility. Surgical correction aims to restore reproductive potential, yet evidence to guide counselling …

Published: Feb. 16, 2026, midnight
Differences in response to dienogest therapy among different phenotypes of endometriosis: A single-center retrospective cohort analysis.

This study aims to investigate the differences in response to dienogest (DNG) therapy among patients with 3 different phenotypes of endometriosis: ovarian endometrioma (OMA), superficial peritoneal endometriosis (SUP), and deep …

Published: Feb. 15, 2026, midnight
Adnexectomy at Vaginal Hysterectomy for Benign Non-prolapse Indications: A National NSQIP Analysis of Practice Patterns and Perioperative Outcomes.

Professional societies recommend opportunistic salpingectomy during vaginal hysterectomy to reduce the risk of ovarian cancer, but it may be technically challenging without uterine prolapse. We examined national patterns, patient and …

Published: Feb. 15, 2026, midnight
Fertility after endometriosis surgery: a systematic review and meta-analysis comparison of primary versus multiple surgical interventions.

Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent …

Published: Feb. 15, 2026, midnight
Associations of baseline characteristics, patient-reported outcomes, and satisfaction with pain therapy with the patient's global impression of change: a prospective cohort study.

Patient-reported outcome measures (PROMs) are key elements of assessing the efficacy of perioperative pain management. Here, we aimed to capture the association of 10 individually reported aspects of patient's specific …

Published: Feb. 13, 2026, midnight
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