Endometriosis is a complex chronic inflammatory disease with an unclear etiology and limited treatment options, severely affecting the reproductive health and quality of life of many women. Histone deacetylases (HDACs), …
In this narrative review, we summarize current evidence regarding the endometrium undergoes cyclic remodeling driven by estrogen (E2) and progesterone (P4) signaling, with precise coordination essential for receptivity and pregnancy …
Endometriosis (EMs) is a chronic neuroinflammatory disorder prevalent in women of reproductive age characterized by heterogeneous clinical manifestations, while conventional Western therapies are limited by obvious adverse reactions and unsatisfactory …
Endometriosis is a chronic oestrogen-dependent condition characterised by the presence of endometrial-like tissue outside the uterus. Although benign, the associated chronic inflammation and fibrosis can result in substantial symptomatic burden, …
Endocrine-disrupting chemicals (EDCs) are ubiquitous environmental contaminants that interfere with hormone signalling and are increasingly linked to adverse reproductive outcomes. This viewpoint highlights emerging evidence that EDC exposure disrupts both …
Endometriosis (EMs) is a common gynecological disorder in women of reproductive age, often presenting with pelvic pain and infertility. Its progression is closely linked to estrogen levels. While hormonal therapies …
The aim was to explore the lived experiences of women diagnosed with endometriosis and receiving care in Spain to understand its impact across multiple areas of their lives. This qualitative …
Endometriosis is an estrogen-dependent disorder characterized by chronic inflammation, immune dysregulation, and altered hormone metabolism. Although gut microbiota-derived metabolites have been implicated in shaping immune microenvironments and lesion development, the …
To assess the prevalence of obstetric and neonatal complications in pregnancies of women with histologically confirmed endometriosis, adenomyosis, or both, compared with the general Dutch population.
Inguinal endometriosis is a very rare extrapelvic form of endometriosis, estimated to occur in only 0.3-0.6% of women with endometriosis. It mostly affects the right round ligament running inside the …