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Reduced GEN1 Expression Is Associated with Elevated DNA Damage and Impaired Proliferation in Endometriosis-Derived Endometrial Organoids.

Endometriosis affects approximately 10% of reproductive-age women and is associated with genomic instability; however, the contribution of specific DNA repair deficiencies remains poorly understood. This study investigated the expression and …

Published: March 26, 2026, midnight
A meta-umbrella review of risk factors for vulvodynia: evidence from demographic, psychosocial, and biomedical domains.

Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associated risk factors are lacking …

Published: March 25, 2026, midnight
Catheter-Directed Sclerotherapy Versus Ovarian Cystectomy for Unilateral Ovarian Endometrioma: A Pilot Randomized Controlled Trial.

Background: Ovarian cystectomy is standard treatment for endometrioma but is associated with decreased ovarian reserve. Catheter-directed sclerotherapy (CDS) is an ovary-sparing image-guided alternative; however, supporting evidence comprises retrospective comparative and …

Published: March 25, 2026, midnight
Medical Treatment for Endometriosis: One Size Does Not Fit All.

Endometriosis is associated with nociceptive pain, as well as peripheral and central sensitization. Evidence-based treatment suggestions for controlling endometriosis should be based on the convergence of the best scientific evidence, …

Published: March 21, 2026, midnight
Gut microbial signatures and stability are associated with a co-diagnosis of endometriosis and inflammatory bowel disease.

Emerging evidence suggests that the gut microbiota plays a crucial role in endometriosis (Endo) and inflammatory bowel disease (IBD). This study aimed to explore gut microbial signatures in women with …

Published: March 21, 2026, midnight
Recurrent catamenial pneumothorax in an adolescent: A case report with review of diagnostic and therapeutic challenges.

Catamenial pneumothorax (CP) is a rare form of spontaneous pneumothorax associated with thoracic endometriosis and is exceptionally uncommon in adolescents. We report a 14-year-old girl with early menarche and heavy …

Published: March 21, 2026, midnight
Exposure to Green Light-emitting Diodes Alleviates Endometriosis-associated Pain in Mice with Induced Deep Endometriosis.

Published: March 19, 2026, midnight
Are the Previously Reported Risk Factors for Endometriosis Actually Associated With Pain and Infertility Rather Than Endometriosis Itself?

Endometriosis is often diagnosed late due to a lack of noninvasive diagnostic tools and the varied presentation of its symptoms. Identifying risk factors for endometriosis is crucial for reducing diagnosis …

Published: March 19, 2026, midnight
Robotic interposition of the mesorectum during low anterior resection of the rectum for endometriosis using tissue perfusion assessment with indocyanine green.

Rectal endometriosis is a serious disease, and its surgical treatment belongs among demanding procedures, often requiring a multidisciplinary approach. It is associated with a significant risk of peri- and postoperative …

Published: March 18, 2026, midnight
SGLT2 Inhibitors and Mortality in Endometriosis With Type 2 Diabetes: A Propensity-Matched Analysis.

Endometriosis is increasingly recognized as a systemic inflammatory condition associated with adverse cardiovascular events, yet glucose-lowering drug selection in this population is not evidence-based.

Published: March 18, 2026, midnight
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