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Endometrial regeneration and the role of the extracellular matrix: mechanisms, challenges, and future perspectives.

Endometrial regeneration is a cornerstone of reproductive health, with the extracellular matrix (ECM) playing a pivotal role in tissue repair, regeneration, and fertility restoration. Dysregulated ECM remodeling is at the …

Published: Aug. 5, 2025, midnight
Laparoscopic ovarian drilling (LOD) versus Step-up gonadotropin therapy in infertile anovulatory PCOS women resistant to sequential letrozole and gonadotropin-based ovulation induction cycles: a randomized controlled trial.

To study the effect of laparoscopic ovarian drilling (LOD) versus step-up gonadotropin therapy on follicular response in infertile anovulatory PCOS women resistant to sequential Letrozole + HMG (Human Menopausal Gonadotropin) …

Published: Aug. 2, 2025, midnight
Linzagolix - new perspectives in the pharmacotherapeutic management of uterine fibroids and endometriosis.

Uterine fibroids and endometriosis are among the most common conditions encountered in gynaecological practice. Fibroids affect 30-70% of women, with up to half experiencing symptoms that significantly impair quality of …

Published: July 28, 2025, midnight
Stage-specific autophagy dynamics in reproductive processes and associated disorders.

Autophagy is a highly conserved eukaryotic process that degrades cytoplasmic material within lysosomes, and plays a crucial role in cellular development, function and homeostasis. Recent studies have increasingly revealed the …

Published: July 28, 2025, midnight
Endometriosis-The scapegoat for pelvic pain?

Cyclic and noncyclic chronic pelvic pain (CPP) represent a major problem for both affected patients and healthcare providers due to its effects on physical and mental health. In times of …

Published: July 27, 2025, midnight
Interplay of Oxidative Stress, Autophagy, and Rubicon in Ovarian Follicle Dynamics: Orchestrating Ovarian Aging.

Organ functions generally decline with age, but the ovary is a prototypical organ that undergoes functional loss over time. Autophagy plays a crucial role in maintaining organ homeostasis, and age-related …

Published: July 27, 2025, midnight
A Complex Case Report of OHVIRA syndrome: Uterine didelphys, obstructed hemivagina, and renal agenesis.

Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome, also known as Herlyn-Werner-Wunderlich syndrome, is a rare congenital anomaly resulting from abnormal development of the Müllerian and Wolffian ducts, characterized by …

Published: July 22, 2025, midnight
Role of AMP-Activated Protein Kinase (AMPK) in Female Reproduction: A Review.

The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signalling pathway regulates cell metabolism, inflammation and the immune response. This signalling pathway is essential for maintaining reproductive homeostasis and influencing steroidogenesis, implantation, …

Published: July 16, 2025, midnight
Multiple lesions of endometriosis in the small intestine treated by the shaving technique: A case report.

A case is reported of endometriosis present in several areas of the small intestine, successfully treated by excision using the conservative technique of shaving the intestinal wall. A 30-year-old woman …

Published: July 13, 2025, midnight
What is Ehlers-Danlos Syndromes (EDS): Lena Dunham's rare condition that affects skin, joints, and more - Times of India

What is Ehlers-Danlos Syndromes (EDS): Lena Dunham's rare condition that affects skin, joints, and more Times of India

Published: July 11, 2025, 6:45 p.m.
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