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Vertebral-spinal endometriosis: a comprehensive narrative review of clinical presentation, diagnostic challenges, and treatment outcomes.

Endometriosis is a chronic inflammatory disease characterized by endometrial-like tissue outside the uterus, affecting approximately 10% of women of reproductive age. While typically confined to the pelvis, lesions may occur …

Published: July 9, 2026, midnight
Multimorbidity in Chronic Overlapping Pain Conditions: From Burden to Integrated Care.

Chronic overlapping pain conditions (COPCs) refer to a set of chronic pain disorders that frequently co-occur and may involve partially overlapping mechanisms. The U.S. National Institutes of Health currently recognizes …

Published: June 22, 2026, midnight
Endometriosis pain index: development of a model to predict poor pain-related quality of life after endometriosis surgery through machine learning analysis of registry data.

Predictive tools are lacking for pain-related outcomes after endometriosis surgery. The objective of this study was to develop and validate a machine learning-based clinical model to predict poor pain-related quality …

Published: Feb. 25, 2026, midnight
Schwann cell C5aR1 co-opts inflammasome NLRP1 to sustain pain in a mouse model of endometriosis.

Over 60% of women with endometriosis experience abdominopelvic pain and broader pain manifestations, including chronic back pain, fibromyalgia, chronic fatigue, vulvodynia, and migraine. Although the imbalance of proinflammatory mediators, including …

Published: Nov. 25, 2024, midnight
Reversal of Endometriosis-Induced Unilateral Ureteral Obstruction and Hydronephrosis With Medical Therapy.

Endometriosis is a common condition among women of reproductive age worldwide, with the urinary tract being the second most frequently affected extragenital organ system, particularly the bladder and ureters. Ureteral …

Published: Nov. 19, 2024, midnight
Spontaneous hemoperitoneum in a 29-week pregnancy with a history of endometriosis: A case report and review of the literature.

Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per …

Published: Nov. 11, 2024, midnight
Chronic overlapping pain conditions and nociplastic pain.

Chronic overlapping pain conditions (COPCs) are a subset of chronic pain conditions commonly comorbid with one another and more prevalent in women and individuals assigned female at birth (AFAB). Pain …

Published: Nov. 4, 2024, midnight
Chronic Overlapping Pain Conditions in people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a sample from the Multi-site Clinical Assessment of ME/CFS (MCAM) study.

Chronic overlapping pain conditions (COPCs), pain-related conditions that frequently occur together, may occur in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This study aimed to …

Published: Oct. 18, 2024, midnight
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