Mitochondrial dysfunction has been demonstrated with a role in pathologically driving various obstetric and gynecological (OB/GYN) diseases, but molecular mediators associating mitochondrial dysfunction with discrete pathologies have not been determined …
Endometriosis and adenomyosis are both characterised by ectopic endometrial-like tissue growing outside the endometrium of the uterus, however, they are ultimately distinct diseases with different pathophysiological mechanisms. Endometriosis and adenomyosis …
Endometriosis is a chronic, systemic condition affecting 5-10% of individuals assigned female at birth. Due to its non-specific symptoms, diagnosis is often delayed.
What is the optimal timing of progesterone exposure to achieve live births for day-6 blastocysts in artificial frozen-thawed embryo transfer (FET) cycles?
Adenomyosis can be categorized using various systems based on its extent, location, and severity. Depending on its location within the endometrium adenomyosis can be classified as intrinsic (inner myometrium) or …
Endometriosis (EMT) is an incurable and painful chronic illness that affects approximately 10% of people assigned female at birth worldwide. Currently, EMT takes on average 5-7 years to diagnose after …
This study aims to investigate the effect of endometriosis (EMs) on fertility and to assess the causal relationship between EMs and fertility using two-sample Mendelian randomization (MR). We conducted an …
Infertility is a common reproductive health issue, associated with increased risks of pregnancy complications. However, shared underlying risk factors such as age, BMI, PCOS, endometriosis, and lifestyle may partly explain …
The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …
Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent …