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The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency.

The LYSET gene encodes the LYSET transmembrane protein, which regulates lysosome biogenesis by activating the mannose-6-phosphate (M6P) pathway. This is an autosomal recessive, ultrarare, and severe progressive skeletal dysplasia with …

Published: March 20, 2026, midnight
Xanthogranulomatous Oophoritis Associated With Chronic Endometriosis: A Clinical Observation.

Xanthogranulomatous oophoritis (XGO) is a rare chronic inflammatory con-dition that can mimic ovarian malignancy both clinically and radiologically. It is characterized by foamy histiocytes and inflammatory infiltrates, often leading to …

Published: March 17, 2026, midnight
Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth.

Endometriosis is a chronic gynecological disorder marked by the growth of endometrial-like tissue outside the uterus, often leading to pelvic pain, inflammation, and infertility. Despite its global prevalence, diagnosis remains …

Published: March 15, 2026, midnight
Neutrophil-To-Lymphocyte and Platelet-To-Lymphocyte Ratios in atypical endometriosis and in Endometriosis-Associated ovarian-Cancer.

Atypical endometriosis (AE) is a histologically distinct entity considered a potential precursor to Endometriosis-Associated Ovarian Cancer (EAOC). Preoperative diagnosis is challenging as imaging often fails to distinguish AE from benign …

Published: March 14, 2026, midnight
Pelvic pain and a missing kidney: Unveiling OHVIRA syndrome with a tubo-ovarian abscess.

Herlyn-Werner-Wunderlich syndrome (OHVIRA syndrome) is a rare congenital anomaly involving the Müllerian and renal systems, classically presenting as uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. Due to its rarity …

Published: March 14, 2026, midnight
Effects of Letrozole Alone or Combined with a GnRH Agonist on Inflammation, Folliculogenesis, and Estrogen Levels in a Rat Model of Peritoneal Endometriosis.

To evaluate the effects of letrozole alone and in combination with a gonadotropin-releasing hormone agonist on inflammatory cytokines, folliculogenesis, and hormonal profiles in a rat model of surgically induced peritoneal …

Published: March 13, 2026, midnight
Three-Dimensional Architecture of Ectopic Epithelium and Vasculature in Ovarian Endometriosis Revealed by Tissue-Clearing Imaging.

Ovarian endometriosis (OEM) is characterised by ectopic endometrial tissue growth within the ovary. In these ectopic lesions, the ectopic epithelium plays a crucial role in OEM progression and has been …

Published: March 12, 2026, midnight
From Vision to Precision: A Systematic Review of Intraoperative Navigation Techniques in Endometriosis Surgery.

To systematically evaluate the clinical evidence on intraoperative navigation techniques in endometriosis surgery.

Published: March 12, 2026, midnight
Novel approaches for PET imaging of endometriosis.

Endometriosis, affecting up to 10% of women, is a chronic estrogen dependent disorder where ectopic endometrial-like tissue causes pelvic pain and infertility. Endometriosis is challenging to diagnose due to symptom …

Published: March 12, 2026, midnight
Adnexal Endometrioid Carcinomas With Sex Cord-Like Morphology are Frequently PAX8-Negative, SOX17-Positive, and Enriched for CTNNB1 Alterations.

Sex cord-like morphology is now a well-known feature of occasional examples of endometrioid carcinoma of the ovary or fallopian tube. Recently, we have observed that these tumors are frequently negative …

Published: March 11, 2026, midnight
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