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E2F1 downregulation promotes lipid droplet accumulation and endometriosis development through impaired MGLL-mediated lipid mobilization.

Endometriosis is a common gynecological disease in which lipid metabolic dysregulation has been increasingly implicated. However, the specific metabolic changes in ectopic lesions and stromal cells remain poorly understood. It …

Published: Sept. 28, 2026, midnight
The Role and Mechanism of Incretins in Gynaecologic Diseases.

Obesity is a major global public health concern closely linked to the development and progression of various gynaecological disorders, particularly polycystic ovary syndrome (PCOS) and endometrial cancer. Incretins, a group …

Published: Sept. 26, 2026, midnight
Artificial intelligence for women's reproductive health: A scoping review of global diagnostic trends, methodological gaps, and a translational research agenda for low-resource settings.

Women's reproductive and endocrine disorders including Polycystic Ovary Syndrome (PCOS), endometriosis, thyroid disorders, infertility, and pregnancy-related complications remain a major global health burden. These conditions are especially difficult to manage …

Published: Sept. 25, 2026, midnight
Contemporary menopausal hormone therapy and thrombotic disease: nationwide nested case-control study.

To investigate associations between current use of menopausal hormone therapy and development of venous thromboembolism, ischaemic stroke, and myocardial infarction.

Published: Sept. 23, 2026, midnight
Establishment of pathology-validated immortalized patient-derived ovarian endometriosis epithelial cell line.

Endometriosis is a heterogeneous gynecological disorder for which experimental model development is often limited by diagnostic ambiguity and the restricted lifespan of primary epithelial cultures. Although immortalization strategies enable long-term …

Published: Sept. 23, 2026, midnight
Evaluating potential risk factors linked to endometriosis: Evidence from a Mendelian randomization study.

Earlier examinations of how risk factors relate to endometriosis (EMT) have largely depended on observational designs, which arrived at conflicting conclusions. The present approach seeks to probe the causal association …

Published: Sept. 20, 2026, midnight
Oncodesign Services and Nexus BioQuest partner on preclinical drug development - Manufacturing Chemist

Oncodesign Services and Nexus BioQuest partner on preclinical drug development Manufacturing Chemist

Published: Sept. 18, 2026, 11:44 a.m.
Oncodesign Services and Nexus BioQuest partner on preclinical drug development - manufacturingchemist.com

Oncodesign Services and Nexus BioQuest partner on preclinical drug development manufacturingchemist.com

Published: Sept. 18, 2026, 11:44 a.m.
The Pathogenesis of Epithelial Ovarian Cancer.

Epithelial ovarian cancer is not a single disease but a group of biologically distinct malignancies that include serous (high-grade and low-grade), endometrioid, clear cell, and mucinous carcinomas, along with other …

Published: Sept. 17, 2026, midnight
Current Evidence and Emerging Directions in Endometriosis Pharmacotherapy: A Systematic Review of Recent Advances.

Background: Endometriosis affects 190 million women worldwide, so there is a need for accessible and more comprehensive knowledge regarding the pharmacotherapeutic options that can be offered to patients. This systematic …

Published: Sept. 17, 2026, midnight
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