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Lactoferrin as a Non-Hormonal Therapeutic Candidate for Endometriosis: Mechanisms and Future Directions.

The pathogenesis and progression of endometriosis may involve a complex combination of multiple factors, including chronic inflammation and oxidative stress. Hormonal therapy, the current standard for pharmacotherapy in endometriosis, causes …

Published: March 5, 2026, midnight
Differential expression of c-kit, E-cadherin, and beta-catenin in endometriosis and normal endometrial tissue.

C-kit, E-cadherin and beta-catenin adhesion molecules and proto-oncogenes are thought to be associated with molecular mechanisms related to the invasion, implantation and persistence of ectopic endometrial cells. Comparing the expression …

Published: March 2, 2026, midnight
Meta-analysis of the effect of goserelin acetate implant on improving hormone levels in patients with endometriosis.

Endometriosis is a hormone-related gynecological disease and characterized by the invasion of endometrial cells outside the uterine cavity.

Published: March 1, 2026, midnight
Endometriosis immune microenvironment timing shifts: from immune escape to immune exhaustion.

Endometriosis(EMS) symptoms, progression, and onset are all linked to the patient's immune system dysfunction. Research on immune cells and their molecular mechanisms has long been a prime focus of EMS …

Published: Feb. 26, 2026, midnight
Endometriosis Is Associated with Increased Serum and Peritoneal Fluid Concentrations of Chromogranin A and Its Derivatives.

Background/Objectives: Endometriosis is a prevalent gynecological illness associated with chronic pain, inflammation, and infertility, as ectopic endometrial lesions are formed. No fully effective treatment is available, and the pathogenesis of …

Published: Feb. 16, 2026, midnight
Development of a three-dimensional culture model of endometrium to study embryo-uterine interactions.

Three-dimensional (3D) culture systems provide physiologically relevant models that better replicate in vivo cell architecture and function compared to the conventional two-dimensional cultures. In reproductive biology, 3D models of endometrial …

Published: Jan. 6, 2026, midnight
Kisspeptins inhibit ectopic endometrial cell invasion and angiogenesis by suppressing PI3K/AKT signaling pathway via CREB5 in endometriosis.

Endometriosis (EMs) is a common gynecological disorder. According to the most widely recognized theory of retrograde menstruation, endometrial cells require completion of three key steps during ectopic implantation: adhesion, invasion, …

Published: Jan. 1, 2026, midnight
Tellimagrandin II Stimulates Inflammasomes by Causing an Accumulation of 3-Aminopropanal, Which Promotes Apoptosis of Endometriotic Cells While Inhibiting Invasion.

Endometriosis is frequently treated with Paeoniae Radix. It contains Tellimagrandin II, which has the role of modulating immunity and anti-tumor. Therefore, we will explore the effects of Tellimagrandin II on …

Published: Dec. 29, 2025, midnight
High inhibition ratio and transformation index of 2 mg dienogest: further evidence for its use in endometriosis treatment.

Endometriosis is a common, chronic disease with a high burden for women, characterised by the implantation of endometrial cells outside the uterus. Many different treatments have been proposed for this …

Published: Dec. 2, 2025, midnight
Network pharmacology prediction of UA in targeting endometriosis progression to endometrial cancer.

Endometriosis is a gynecological disorder predominantly affecting women of reproductive age and is considered a potential risk factor for the development of endometrial cancer. However, the molecular mechanisms underlying the …

Published: Nov. 26, 2025, midnight
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