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Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 2024.

Spironolactone, eplerenone, and finerenone are three commonly used mineralocorticoid receptor antagonists (MRAs) with cardioprotective and renoprotective effects. However, comparative real-world safety evaluations remain limited. This study aimed to assess and …

Published: Jan. 7, 2026, midnight
Analyzing real-world adverse events of spironolactone with the FAERS database.

Spironolactone, a potassium-sparing diuretic, is commonly prescribed for conditions such as heart failure, hypertension, and hyperaldosteronism. This study aims to explore and analyze the safety profile of spironolactone by examining …

Published: Sept. 17, 2025, midnight
Real-World Study on Adverse Drug Reactions of Pembrolizumab in Endometrial Cancer Treatment: Insights from the FAERS Database - Frontiers

Real-World Study on Adverse Drug Reactions of Pembrolizumab in Endometrial Cancer Treatment: Insights from the FAERS Database Frontiers

Published: Aug. 6, 2025, 2:27 p.m.
Pharmacovigilance study of the association between progestogen and depression based on the FDA adverse event reporting System (FAERS).

Progestogens commonly used in the clinic include levonorgestrel, etonogestrel, medroxyprogesterone, hydroxyprogesterone, progesterone, desogestrel, and megestrol. Progestogens are widely used for contraception and the treatment of endometriosis, threatened abortion and other …

Published: Jan. 8, 2025, midnight
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