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Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 2024.

Spironolactone, eplerenone, and finerenone are three commonly used mineralocorticoid receptor antagonists (MRAs) with cardioprotective and renoprotective effects. However, comparative real-world safety evaluations remain limited. This study aimed to assess and …

Published: Jan. 7, 2026, midnight
Causal relationship between diet and common female diseases: a comprehensive Mendelian randomization study.

This study aimed to investigate the causal relationship between dietary habits and nine common diseases with high female prevalence using a two-sample Mendelian randomization (MR) approach.

Published: Dec. 28, 2025, midnight
An Overview of Essential Nutritional Strategies and Products in the Treatment of Endometriosis.

Recent reports on the co-occurrence of allergies and endometriosis have provided grounds for expanding research in this area, suggesting that diagnostics should be extended to women with endometriosis. However, numerous …

Published: Dec. 26, 2025, midnight
Endometriosis lesion growth inhibition and immune modulation function of thymol in vitro and in vivo.

Thymol, a phenolic monoterpene derivative found in the essential oil of Thymus vulgaris L., Lamiaceae, is currently under investigation for potential applications in pharmaceuticals, functional foods, and cosmetics. Despite ongoing …

Published: Nov. 17, 2025, midnight
Mechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis.

Endometriosis involves oestrogen-dependent chronic inflammation and the abnormal proliferation of ectopic endometrial tissue. Conventional hormonal therapies suppress systemic oestrogen, but do not fully address local oxidative and inflammatory signalling. This …

Published: Nov. 12, 2025, midnight
Mediterranean diet adherence and healthy diet indicator might decrease odds of endometriosis.

Diet may play a crucial role in managing endometriosis. Dietary interventions could help women with endometriosis improve their quality of life and reduce pain symptoms. The aim of this study …

Published: Oct. 21, 2025, midnight
Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms.

Oxidative stress plays a central role in reproductive disorders, with food bioactive compounds offering therapeutic potential through their antioxidant properties. This review examines antioxidant active ingredients from plant-based foods and …

Published: Oct. 9, 2025, midnight
Impact of endocrine disruptors on female fertility: an update.

Endocrine disruptors (EDs) are a heterogeneous group of natural or synthetic chemicals capable of interfering with hormonal regulation. Widely present in plastics, cosmetics, pesticides, food packaging, and household products, they …

Published: Oct. 7, 2025, midnight
The Role of Nutrition in Endometriosis Prevention and Management: A Comprehensive Review.

Endometriosis is a chronic gynecological condition defined by the ectopic presence of endometrial-like tissue outside the uterine cavity, often resulting in debilitating symptoms and significant impacts on quality of life. …

Published: Sept. 30, 2025, midnight
Triptorelin associated adverse events evaluated using FAERS pharmacovigilance data.

Triptorelin, a gonadotropin-releasing hormone(GnRH) agonist, is approved by the US Food and Drug Administration(FDA) for treating advanced prostate cancer, endometriosis, and central precocious puberty(CPP) in children aged ≥ 2 years. …

Published: Sept. 1, 2025, midnight
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