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The role of insulin-like growth factor binding proteins in TGF-β1-induced fibroblast-myofibroblast transition during endometriosis fibrosis.

Fibrosis is a defining feature of endometriosis (EMS). Our previous single-cell RNA sequencing (scRNA-seq) revealed myofibroblasts (MFBs) as the predominant cells in ectopic endometrium (ECE), mainly derived from fibroblast-to-myofibroblast transition …

Published: Jan. 9, 2026, midnight
The Role of Astaxanthin as an Antioxidant and Anti-Inflammatory Agent in Human Health: A Systematic Review.

This systematic review aimed to summarize the effects of astaxanthin (ASX) supplementation on oxidative stress, inflammation, and metabolic regulation in human studies. A systematic search was conducted in Scopus, Web …

Published: Jan. 9, 2026, midnight
Microbiota and infertility: a translational review of mechanisms and clinical applications in assisted reproduction.

Infertility constitutes a major global health concern, affecting approximately 17.5% of couples of reproductive age. Although advances in assisted reproductive technologies (ART) have expanded treatment options, success rates remain highly …

Published: Jan. 5, 2026, midnight
Diabetes drug can also protect heart and liver? Doc answers as Mounjaro slashes man’s insulin by 70% - Times of India

Diabetes drug can also protect heart and liver? Doc answers as Mounjaro slashes man’s insulin by 70% Times of India

Published: Nov. 25, 2025, 11:30 a.m.
Diabetes drug can also protect heart and liver? Doc answers as Mounjaro slashes man’s insulin by 70% - The Times of India

Diabetes drug can also protect heart and liver? Doc answers as Mounjaro slashes man’s insulin by 70% The Times of India

Published: Nov. 25, 2025, 11:30 a.m.
Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway.

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome proliferator‑activated receptor α (PPARα) and …

Published: Oct. 31, 2025, midnight
Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms.

Oxidative stress plays a central role in reproductive disorders, with food bioactive compounds offering therapeutic potential through their antioxidant properties. This review examines antioxidant active ingredients from plant-based foods and …

Published: Oct. 9, 2025, midnight
Active belly fat linked to aggressive endometrial cancer: Study | Inflammation can also induce insulin resistance | Inshorts - Inshorts

Active belly fat linked to aggressive endometrial cancer: Study | Inflammation can also induce insulin resistance | Inshorts Inshorts

Published: Oct. 5, 2025, 6:18 p.m.
Di-(2-ethylhexyl) phthalate induces endometriosis by modulating IGF-1 m6A methylation via the intestinal Odoribacter-butyric acid axis in female rats.

Endometriosis, a complex gynecological disorder characterized by aberrant growth of endometrial tissue outside the uterine cavity, poses a significant challenge to women's health. Emerging evidence implicates environmental pollutants, particularly di-(2-ethylhexyl) …

Published: Sept. 23, 2025, midnight
New Perspectives on the Use of Resveratrol in the Treatment of Metabolic and Estrogen-Dependent Conditions Through Hormonal Modulation and Anti-Inflammatory Effects.

Estrogen-dependent conditions, such as endometriosis, adenomyosis, lipedema, polycystic ovary syndrome, and breast cancer, are intimately involved with hormonal changes related to estrogen and their receptors. These conditions can be expressed …

Published: Aug. 27, 2025, midnight
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