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TREM2 Deficiency Attenuates Endometriosis Progression by Inhibiting M2 Polarization of SpMs and Suppressing SIRPα to Enhance Phagocytosis.

Endometriosis (EMS) is characterised by a disrupted peritoneal immune microenvironment where M2 macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-seq (ScRNAseq) of the peritoneal macrophages from EMS patient …

Published: Aug. 5, 2026, midnight
Recent insights in pathogenesis of endometriosis with focus on gut microbiota.

EMs is a chronic, estrogen-dependent systemic inflammatory disorder defined by the ectopic implantation of endometrial glands and stroma and is frequently associated with dysmenorrhea, chronic pelvic pain, infertility, and substantial …

Published: Aug. 4, 2026, midnight
Q&A: Are environmental chemicals and endometrial cancer linked? - Medical Xpress

Q&A: Are environmental chemicals and endometrial cancer linked? Medical Xpress

Published: July 30, 2026, 11:20 a.m.
Q&A: Are environmental chemicals and endometrial cancer linked? - medicalxpress.com

Q&A: Are environmental chemicals and endometrial cancer linked? medicalxpress.com

Published: July 30, 2026, 11:20 a.m.
Q&A: Are environmental chemicals and endometrial cancer linked? - The Pennsylvania State University

Q&A: Are environmental chemicals and endometrial cancer linked? The Pennsylvania State University

Published: July 28, 2026, 1 p.m.
Elucidating behavioral and environmental barriers to clinicians' engagement in endometriosis diagnostic practices: a mixed-methods scoping review.

Endometriosis is an estrogen-dependent chronic systemic inflammatory disease that affects 10 % of people assigned female at birth. Despite its prevalence, mean diagnostic delay is 4-11 years. Although much research …

Published: July 27, 2026, midnight
p53-mediated epigenetic regulation in the pathogenesis of endometriosis.

Endometriosis (EMs) is a common gynecological disorder affecting reproductive‑aged women, characterized by ectopic endometrial growth and chronic pelvic pain that severely impairs quality of life. Although its pathogenesis remains incompletely …

Published: July 21, 2026, midnight
Assessing the female urogenital-rectal axis microbiome: focus on endometriosis and recurrent implantation failure.

Emerging evidence suggests microbial dysbiosis may contribute to gynaecological pathologies, including endometriosis and recurrent implantation failure (RIF). The vaginal microbiome is well-characterised, with Lactobacillus-dominance as a hallmark of health, yet …

Published: July 21, 2026, midnight
Rheumatic Heart Disease: Inflammation, Immune Pathways, Valve Remodeling, and the Promise of SGLT2 Inhibitors.

Rheumatic heart disease (RHD) remains the leading cause of acquired valvular heart disease in low- and middle-income countries, affecting an estimated 40 million individuals and disproportionately affecting children and young …

Published: July 16, 2026, midnight
N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence.

Endometriosis is a chronic inflammatory and estrogen-dependent disease in which oxidative stress, immune dysregulation, and lesion-supportive microenvironmental signaling contribute to lesion development. N-acetylcysteine (NAC), a glutathione-replenishing and redox-modulating agent, has …

Published: July 16, 2026, midnight
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