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Is endometriosis a progressive disease?

Whether endometriosis is a progressive disease remains debated. Central to this debate is understanding the natural history of endometriotic lesions, which are essentially wounds undergoing repeated tissue injury and repair. …

Published: March 20, 2026, midnight
Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth.

Endometriosis is a chronic gynecological disorder marked by the growth of endometrial-like tissue outside the uterus, often leading to pelvic pain, inflammation, and infertility. Despite its global prevalence, diagnosis remains …

Published: March 15, 2026, midnight
Pelvic pain and a missing kidney: Unveiling OHVIRA syndrome with a tubo-ovarian abscess.

Herlyn-Werner-Wunderlich syndrome (OHVIRA syndrome) is a rare congenital anomaly involving the Müllerian and renal systems, classically presenting as uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. Due to its rarity …

Published: March 14, 2026, midnight
From the margins to the mainstream: The quiet force in innovation of minimally invasive therapy.

Published: March 13, 2026, midnight
Novel approaches for PET imaging of endometriosis.

Endometriosis, affecting up to 10% of women, is a chronic estrogen dependent disorder where ectopic endometrial-like tissue causes pelvic pain and infertility. Endometriosis is challenging to diagnose due to symptom …

Published: March 12, 2026, midnight
Adnexal Endometrioid Carcinomas With Sex Cord-Like Morphology are Frequently PAX8-Negative, SOX17-Positive, and Enriched for CTNNB1 Alterations.

Sex cord-like morphology is now a well-known feature of occasional examples of endometrioid carcinoma of the ovary or fallopian tube. Recently, we have observed that these tumors are frequently negative …

Published: March 11, 2026, midnight
HIGH VERSUS STANDARD DOSE FOLIC ACID SUPPLEMENTATION FOR MISCARRIAGE PREVENTION: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.

To assess whether high-dose folic acid supplementation (4-5 mg/day), initiated before conception, reduces the risk of miscarriage and improves pregnancy rates compared to standard-dose supplementation (0.4 mg/day).

Published: March 11, 2026, midnight
Potential Harm of the Use of the Word "Benign" in Gynecologic Care.

"Benign gynecologic conditions" is an umbrella term widely used to describe prevalent conditions such as endometriosis, adenomyosis, uterine fibroids, and genitourinary syndrome of menopause in clinical guidelines, research, reviews, and …

Published: March 11, 2026, midnight
Retrospective evaluation of the mr#ENZIAN classification's applicability in the pre-operative assessment of complex endometriosis: a compartment-dependent challenge.

Pelvic MRI is increasingly performed as a second-line investigation in suspected complex cases of endometriosis, to precisely localize lesions and to optimise surgical planning. To facilitate MRI evaluation and inter-disciplinary …

Published: March 9, 2026, midnight
Hidden in the Scar: A Rare Case of Vulvar Endometriosis Mimicking Bartholin's Cyst at an Episiotomy Site.

Vulvar endometriosis is an exceptionally rare manifestation of extrapelvic endometriosis, particularly when located at the site of a prior episiotomy. Often misdiagnosed as more common vulvar pathologies, these lesions may …

Published: March 9, 2026, midnight
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