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Safety and efficacy of hormonal therapies used to treat endometriosis in women suffering migraine.

Hormonal therapy is the cornerstone of long-term endometriosis management, especially for women deferring surgery. In patients with comorbid migraine - a common, disabling condition - therapeutic choices must balance efficacy …

Published: Feb. 2, 2026, midnight
[A targeted approach to cardiovascular risk in women: towards improved screening and prevention].

In women, cardiovascular risk is influenced by factors that differ from those in men, including hormonal status, obstetric complications, and specific conditions such as migraine, endometriosis, or chronic inflammatory diseases. …

Published: Jan. 6, 2026, midnight
Botulinum toxin for endometriosis-associated chronic pelvic pain: a randomised, double-masked, parallel, phase 2 trial.

Chronic pelvic pain affects one in four women. Botulinum toxin, approved for chronic migraine and cervical dystonia pain, is an emerging treatment for other pain conditions. We evaluated intramuscular pelvic …

Published: Jan. 5, 2026, midnight
The interplay between migraine, endometriosis and polycystic ovarian syndrome: A systematic review.

BackgroundMigraine and gynecological conditions, such as endometriosis (EDM) and polycystic ovarian syndrome (PCOS), are highly prevalent among females and appear to influence each other, with a potential shared pathophysiological mechanism. …

Published: Dec. 12, 2025, midnight
Impact of visceral pain on migraine symptoms in comorbid patients: a retrospective observational study.

Visceral pain and migraine, especially at a high frequency/chronic, are frequent comorbidities, but little is known about their mutual influences. This study investigated if visceral pain-migraine comorbidity involves higher migraine …

Published: Oct. 16, 2025, midnight
Inflammatory Cytokine Signatures Are Associated With Disease Burden and Comorbidity of Episodic Migraine and Endometriosis.

The aim of this study was to characterize inflammatory cytokine profiles in women diagnosed with episodic migraine, endometriosis, or both conditions and to determine how these cytokine patterns relate to …

Published: Oct. 3, 2025, midnight
Multi-ancestry genome-wide association study of endometriosis and its clinical manifestations in ~1.4 million women: translating gene discovery into pathogenic mechanisms and therapeutic targets.

We conducted a multi-ancestry genome-wide association study of endometriosis and adenomyosis in almost 1.4 million women, including 105,869 cases, aiming to expand endometriosis loci discovery across ancestries, dissect symptom-specific effects, …

Published: Sept. 5, 2025, midnight
Endometriosis, Raynaud's Syndrome and Migraine: A Retrospective Study of 12 Million Women.

Our study focused on evaluating a possible relationship between endometriosis, Raynaud's syndrome or migraine among women.

Published: April 4, 2025, midnight
Postpartum Depression in Patients with Chronic Migraine: A Retrospective, Observational Analysis.

Purpose: To evaluate how migraine impacts the risk for postpartum depression (PPD) in women of reproductive age as well as the effect of comorbidities on this risk. Methods: This is …

Published: April 2, 2025, midnight
[Women's Life Stages and Migraine].

Migraine is a neurological disorder characterized by a high degree of disruption to life. The prevalence of migraines is high among women in their 20s to 40s. The hormonal milieu …

Published: March 12, 2025, 12:13 a.m.
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