Latest Articles

Prostate-specific membrane antigen immunostaining in endometriosis: preliminary findings and a case of in vivo imaging with gallium-68 positron emission tomography/computed tomography.

Exploring the mechanisms of luteolin in treating polycystic ovary syndrome and endometriosis via network pharmacology, molecular docking, and molecular dynamics simulation.

This study aims to elucidate the molecular mechanisms underlying luteolin's therapeutic effects on polycystic ovary syndrome (PCOS) and endometriosis (EM), thereby providing a theoretical foundation for developing novel treatment strategies. …

Functional Impairment of Activated Regulatory T Cells as a Central Immunological Defect in Endometriosis.

Endometriosis is increasingly recognized as a disorder of impaired reproductive immune tolerance rather than solely an endocrine disease. Although previous studies have reported inconsistent findings regarding the number of regulatory …

Plasma proteomic signature of the human menstrual cycle.

The menstrual cycle is one of the most fundamental biological rhythms in human physiology, yet its systemic molecular changes remain poorly understood. Here we show that the menstrual cycle is …

Social Media Health Information Formats and Endometriosis Treatment-Seeking Intentions: A Randomized Controlled Trial.

BackgroundDespite many women learning about endometriosis on social media, posts about the condition often fail to reflect current evidence. With the content and credibility of online health messages being found …

CHCHD2: a bi-organellar fulcrum of mitochondrial homeostasis and reproductive pathology.

Mitochondrial dysfunction has been demonstrated with a role in pathologically driving various obstetric and gynecological (OB/GYN) diseases, but molecular mediators associating mitochondrial dysfunction with discrete pathologies have not been determined …

Magnetic Resonance Imaging as a Non-Surgical Predictor of Endometriosis Fertility Index Surgical Factors.

Endometriosis affects 6%-10% of women of reproductive age and is associated with chronic pelvic pain, infertility, and impaired quality of life. The endometriosis fertility index (EFI) predicts spontaneous pregnancy postoperatively, …

Non-invasive endometriosis staging prediction using integrated radiomics and spatiotemporal transformer model based on dynamic contrast-enhanced MRI.

Precise staging of endometriosis remains a clinical challenge, as current diagnosis depends almost entirely on laparoscopic visualization-an invasive procedure marked by considerable inter-observer disagreement and diagnostic delays. Existing non-invasive approaches, …

Mechanisms of reproductive toxicity and endocrine disruption of bisphenols and per- and polyfluoroalkyl substances (PFAS): Implications for women's reproductive health.

Bisphenols and per- and polyfluoroalkyl substances (PFAS) are ubiquitous environmental endocrine-disrupting chemicals with widespread human exposure and growing concern regarding their reproductive toxicity. This review integrates current experimental and epidemiologic …

Is colorectal resection necessary to improve pain and fertility outcomes in patients with deep endometriosis?

Bowel endometriosis is often considered an indication for extensive surgical management, including colorectal resection, in women undergoing surgery for concomitant endometriosis at other sites. However, several contemporary studies show little …