Women with endometriosis often face difficulty becoming pregnant, mainly when their ovaries produce only a small number of eggs. In assisted fertility treatments, hormones are used to help eggs mature …
Female fertility has long been explained through observation of the ovarian follicle: the number of residing follicles and the quality of the oocyte. This review argues that the tissue surrounding …
The meiotic spindle is essential for accurate chromosome segregation during oocyte maturation and fertilization, and its alteration might be considered a major contributor to age-related aneuploidy and reproductive failure. Spindle …
To investigate whether ovarian response to controlled ovarian stimulation (COS) for medical fertility preservation differs according to the underlying indication, comparing oncological and benign conditions.
Endometriosis is a challenging gynaecological condition that can lead to infertility. This unique narrative review summarises the impact of endometriosis, focusing on oocyte quality, its subcellular and molecular mechanisms, clinical …
A broad range of genetic and epigenetic factors contributes to female infertility, a substantial proportion of which is related to ovulatory disorders. Any factor that disrupts the normal function of …
How do unoperated ovarian endometriomas affect ovarian response during ovarian stimulation cycles?
Premature ovarian insufficiency (POI) is defined as loss of ovarian function before the age of 40 years. It has a profound impact on patients' quality of life, particularly due to …
Endometriosis (EMS) is an oestrogen-dependent chronic inflammatory disease that primarily manifests as chronic pelvic pain and infertility. EMS-associated infertility is closely linked to diminished ovarian function and oocyte quality, with …