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Pathogenic Properties of Human Endometriotic Epithelial Cells Require Steroid Receptor Coactivator-2.

Commonly diagnosed in reproductive-age women, endometriosis is causally linked to subfertility, infertility, and chronic pelvic pain. Although theories exist on the etiopathogenesis of endometriosis, our understanding of its cellular and …

Published: Oct. 6, 2026, midnight
Diagnosing endometriosis in adolescents using ultrasound and MRI: A scoping review of imaging approach and implementation considerations.

Imaging is increasingly used for adult endometriosis, but evidence supporting adolescent imaging approaches remains unclear. This scoping review mapped evidence on imaging-based diagnosis of endometriosis in adolescents and young people, …

Published: Oct. 5, 2026, midnight
Opiranserin (VVZ-149): what's new in analgesics.

Opiranserin (VVZ-149) is a novel non-opioid, non-steroidal intravenous analgesic with triple antagonistic activity at glycine transporter 2 (GlyT2), purine 2 receptor 3 (P2X3), and serotonin receptor (5-HT2A). Its half-maximal inhibitory …

Published: Oct. 2, 2026, midnight
Sex-specific mechanisms of chronic pain.

For decades, we have known that women, especially younger women, are disproportionately affected by pain disorders, including irritable bowel syndrome, endometriosis, menstrual migraines, fibromyalgia, osteoarthritis, and neuropathic pain, all of …

Published: Oct. 1, 2026, midnight
The Most Impactful Symptom of Endometriosis Questionnaire (MISE-Q): a cognitive interview study.

Endometriosis is a condition with symptoms that vary widely, often affecting daily activities and quality of life. A patient-centered approach to identifying and measuring the most important symptoms has been …

Published: Sept. 30, 2026, midnight
Mesonephric and Mesonephric-Like Proliferations of the Gynecologic Tract.

Mesonephric remnants are vestiges of Wolffian ducts located adjacent to the Müllerian ducts. Proliferations arising from these remnants are uncommon and classified as benign, including mesonephric hyperplasia, Gartner and rete …

Published: Sept. 30, 2026, midnight
[A national questionnaire survey of the current status of diagnosis and treatment of endometriosis in China in 2024].

Objective: To investigate the current status of clinical practice and the implementation of existing guidelines for endometriosis in China, and to provide a reliable basis for relevant continuing medical education …

Published: Sept. 29, 2026, midnight
E2F1 downregulation promotes lipid droplet accumulation and endometriosis development through impaired MGLL-mediated lipid mobilization.

Endometriosis is a common gynecological disease in which lipid metabolic dysregulation has been increasingly implicated. However, the specific metabolic changes in ectopic lesions and stromal cells remain poorly understood. It …

Published: Sept. 28, 2026, midnight
Use of symptom-reporting tools to support endometriosis identification and management in primary care: a realist synthesis.

Endometriosis affects 5-10% of women of reproductive age and is associated with chronic pain, infertility and reduced quality of life. Symptom Reporting Tools (SRTs) may support identification and management in …

Published: Sept. 28, 2026, midnight
Machine learning-assisted design of a novel crocin-loaded poloxamer 407/hyaluronic acid in situ forming hydrogel for endometriosis treatment: in vitro characterization and in vivo efficacy evaluation.

Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the …

Published: Sept. 28, 2026, midnight
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