Latest Articles

[Activation of the CaMKKβ/AMPK/HIF-1α signaling pathway promotes angiogenesis in endometriosis by regulating mitophagy].

To investigate whether the CaMKKβ/AMPK/HIF-1α signaling pathway participates in angiogenesis in endometriosis by regulating mitophagy.

The 'missed disease' that affects 190 million: endometriosis drug shows early promise.

The Most Impactful Symptom of Endometriosis Questionnaire (MISE-Q): a cognitive interview study.

Endometriosis is a condition with symptoms that vary widely, often affecting daily activities and quality of life. A patient-centered approach to identifying and measuring the most important symptoms has been …

[A national questionnaire survey of the current status of diagnosis and treatment of endometriosis in China in 2024].

Objective: To investigate the current status of clinical practice and the implementation of existing guidelines for endometriosis in China, and to provide a reliable basis for relevant continuing medical education …

E2F1 downregulation promotes lipid droplet accumulation and endometriosis development through impaired MGLL-mediated lipid mobilization.

Endometriosis is a common gynecological disease in which lipid metabolic dysregulation has been increasingly implicated. However, the specific metabolic changes in ectopic lesions and stromal cells remain poorly understood. It …

Simvastatin and Primaquine Identified as Potential Endometriosis Therapeutics via a Novel Epithelial-Stromal Assembloid Drug Screening Assay.

Endometriosis is an estrogen-driven, inflammatory disorder affecting ~10% of menstruators, causing severe pain. Current treatments that reduce estrogen or inflammation have inconsistent efficacy and poor tolerability. Therapies identified via drug-repositioning …

YTHDF3 promotes angiogenesis in endometriosis by enhancing the translation efficiency of PFKFB3.

Angiogenesis plays a critical role in the progression of endometriosis, with enhanced glycolysis accelerating pathological angiogenesis. Prior research has identified a central role for N6-methyladenosine (m6A) modification in regulating glycolytic …

Arimoclomol-loaded Pluronic F127 nanomicelles in experimental endometriosis: drug incorporation, in vitro release, and early morphological and histological responses.

Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by ectopic endometrial-like glands and stroma, persistent pelvic inflammation, pain, infertility, and frequent recurrence. The limited availability of nonhormonal and lesion-directed therapies …

Evaluating the Effects of a Health Action Process Approach (HAPA)-Based Intervention on Adolescents' Menstrual Health Behaviors.

PurposeThis study evaluated the effects of a school-based intervention grounded in the Health Action Process Approach (HAPA) on adolescents' intentions to seek medical consultation for menstrual health concerns.DesignQuasi-experimental pre-post intervention …

Nutrition and Endometriosis: Current Evidence on Dietary Risk Factors and Clinical Impact - A Narrative Review.

Endometriosis (EM) is a severe chronic inflammatory disease characterized by the presence of endometrium-like tissue outside the uterine cavity, causing pain and significantly reducing quality of life. Worldwide, around 10% …