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Opiranserin (VVZ-149): what's new in analgesics.

Opiranserin (VVZ-149) is a novel non-opioid, non-steroidal intravenous analgesic with triple antagonistic activity at glycine transporter 2 (GlyT2), purine 2 receptor 3 (P2X3), and serotonin receptor (5-HT2A). Its half-maximal inhibitory …

Published: Oct. 2, 2026, midnight
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Analgesia Analgesics Chronic Cough Chronic Pain Endometriosis Glycine Plasma Membrane Transport Proteins Neuralgia Nociceptive Pain Overactive Patient-Controlled Purinergic P2x Receptor Antagonists Receptors Serotonin Spinal Ganglion Urinary Bladder
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