Opiranserin (VVZ-149) is a novel non-opioid, non-steroidal intravenous analgesic with triple antagonistic activity at glycine transporter 2 (GlyT2), purine 2 receptor 3 (P2X3), and serotonin receptor (5-HT2A). Its half-maximal inhibitory …
For decades, we have known that women, especially younger women, are disproportionately affected by pain disorders, including irritable bowel syndrome, endometriosis, menstrual migraines, fibromyalgia, osteoarthritis, and neuropathic pain, all of …
Deep endometriosis (DE) may be associated with chronic pelvic pain, pelvic floor dysfunction, sexual dysfunction, psychological distress, and impaired quality of life, though relationships remain poorly characterized. We investigated associations …
Endometriosis is a chronic disease for which no curative treatment currently exists. The available palliative treatments are not without side effects and must be tailored to the individual expectations and …
Objective: To investigate the current status of clinical practice and the implementation of existing guidelines for endometriosis in China, and to provide a reliable basis for relevant continuing medical education …
This study evaluates the surgical feasibility, safety and early perioperative outcomes of Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) for benign gynecological conditions in patients with histologically confirmed concomitant endometriosis.
Endometriosis is characterised by the growth of abnormal endometrial tissue outside the uterus and chronic inflammation. Increasing evidence suggests that placenta extracellular vesicles (EVs) inhibit the growth and migration of …
Minimally invasive surgery is the gold standard for the surgical treatment of endometriosis. However, controversy remains in the literature regarding the perioperative benefits of robotic-assisted surgery compared to laparoscopic surgery, …
Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the …
Müllerian adenosarcoma (MA) is a rare malignant tumor of the female reproductive system. Owing to the limited number of clinical cases and the absence of characteristic clinical manifestations, its clinical …