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Motivation to join and supportive activity within online health communities among patients with persistent pain: A survey-based examination.

Online Health Communities (OHCs) are key platforms for people seeking medical information and social support. Individuals with persistent pain often use these communities to better understand their condition, share experiences, …

Published: June 18, 2026, midnight
Ceramide: a pivotal lipid mediator shaping female reproductive homeostasis and pathophysiology.

Ceramide, a central hub in sphingolipid metabolism, serves as a critical bioactive signalling mediator that integrates lipid metabolism with multiple signalling pathways, primarily promoting autophagy and apoptosis. It influences female …

Published: June 15, 2026, midnight
An ensemble machine learning model based on magnetic resonance imaging features for diagnosing deep infiltrating endometriosis.

To address the need for more objective and reproducible preoperative diagnosis of deep infiltrating endometriosis (DIE), this study aimed to develop and validate a weighted ensemble machine learning (ML) model …

Published: May 29, 2026, midnight
Parabacteroides goldsteinii and its metabolite 7-KLCA attenuate endometriosis via TGR5 to reprogram macrophages by modulating the PPARγ/GPR132 axis.

Endometriosis (EMS) remains understudied in effective management strategies. The interplay between macrophage dysfunction and microbiota-derived immune signals emerges as a potential mechanism in EMS pathogenesis, suggesting its relevance for future …

Published: May 22, 2026, midnight
From gut-reproductive microbiota to ferroptosis: a comprehensive insight into the molecular-pathogenicity of endometriosis.

Endometriosis (EMS) is a highly heterogeneous chronic gynecological disease characterized by pain, infertility, and relapse, with its etiology and pathogenesis not yet fully elucidated. Traditional theories, including "retrograde menstruation," "implantation …

Published: May 22, 2026, midnight
Challenging the paradigm that neonatal uterine bleeding represents the first menstrual episode.

Neonatal uterine bleeding (NUB) has been hypothesized as a relatively common early-life event potentially linked to the later development of endometriosis through retrograde menstruation. However, its true prevalence and biological …

Published: May 18, 2026, midnight
Common Gynecologic Issues in Patients Post-Kidney Transplantation.

Advances in kidney transplantation have transformed survival and quality of life for women with end-stage renal disease, necessitating a focus on long-term health care for this population. Female kidney transplant …

Published: May 15, 2026, midnight
A review on shared genetic architecture of endometriosis and migraine: from pleiotropy to convergent inflammatory pathways.

The comorbidity between endometriosis and migraine has long been recognized clinically, yet a unifying pathophysiological explanation has remained elusive. Traditional models, centered on hormonal fluctuations or secondary inflammation are lacking …

Published: May 15, 2026, midnight
Targeting the Wnt signaling network in endometriosis: mechanistic insights and translational opportunities.

Endometriosis is a chronic gynecological disorder defined by the growth of endometrial-like tissue outside the uterus, driven by estrogen-dependent inflammation and progressive fibrosis. According to available data, remodeling and persistent …

Published: May 8, 2026, midnight
Peer Support in Online Women's Health Communities: Mixed Methods Formative Analysis of Reddit Discourse.

Stigmatized women's health issues, such as polycystic ovary syndrome (PCOS) and endometriosis, are often marginalized or dismissed in traditional clinical settings. This drives individuals to seek peer support in anonymous …

Published: May 4, 2026, midnight
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