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TREM2 Deficiency Attenuates Endometriosis Progression by Inhibiting M2 Polarization of SpMs and Suppressing SIRPα to Enhance Phagocytosis.

Endometriosis (EMS) is characterised by a disrupted peritoneal immune microenvironment where M2 macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-seq (ScRNAseq) of the peritoneal macrophages from EMS patient …

Published: Aug. 5, 2026, midnight
Association of Autoimmune Hyperthyroidism and Endometriosis, With an Endometrioma Rupture as a Complication: A Case Report and Review of the Literature.

This case report examines the association between autoimmune thyroid disease, more commonly known as Graves' disease, and endometriosis with a focus on the complication of an endometrioma rupture. The interplay …

Published: Aug. 5, 2026, midnight
Recent insights in pathogenesis of endometriosis with focus on gut microbiota.

EMs is a chronic, estrogen-dependent systemic inflammatory disorder defined by the ectopic implantation of endometrial glands and stroma and is frequently associated with dysmenorrhea, chronic pelvic pain, infertility, and substantial …

Published: Aug. 4, 2026, midnight
Activin A is a functional component of the anti-endometriotic drug Endoferin.

Endometriosis is a prevalent gynecological condition affecting up to 25-40% of women with infertility. Endoferin, a protein complex derived from the bovine ovarian follicles, has demonstrated high efficacy in clinical …

Published: July 31, 2026, midnight
Elucidating behavioral and environmental barriers to clinicians' engagement in endometriosis diagnostic practices: a mixed-methods scoping review.

Endometriosis is an estrogen-dependent chronic systemic inflammatory disease that affects 10 % of people assigned female at birth. Despite its prevalence, mean diagnostic delay is 4-11 years. Although much research …

Published: July 27, 2026, midnight
Are gastrointestinal, gynecological and urogenital chronic overlapping pain conditions (COPCs) predisposing or perpetuating factors for orofacial pain (OFP)? A systematic review.

Orofacial pain (OFP) is a multidimensional clinical problem that includes conditions such as temporomandibular disorders (TMD). It is often associated with chronic overlapping pain conditions (COPCs), including gastrointestinal, gynecological and …

Published: July 25, 2026, midnight
Inflammation, Estrogen, and Matrix Remodeling in Female Reproductive Health: From Crosstalk Mechanisms to Translational Diagnostics.

The female reproductive system is a hormonally driven, immune-active, and structurally dynamic system in which estrogen signaling, inflammation, and extracellular matrix (ECM) remodeling interact to support essential reproductive processes. Cyclical …

Published: July 24, 2026, midnight
Microbiome and chronic pelvic pain in women: a mini-review.

Chronic pelvic pain (CPP) is a prevalent, disabling syndrome encompassing overlapping disorders such as endometriosis/adenomyosis, bladder pain syndrome/interstitial cystitis, irritable bowel syndrome, vulvodynia, and myofascial pain syndrome. Despite distinct clinical …

Published: July 24, 2026, midnight
Longitudinal trends in general, central, and visceral adiposity indices among women with endometriosis: a population-based study.

Previous studies have suggested the close link between endometriosis and body size index. However, there are inconsistent associations between central, general, and visceral adiposity index and endometriosis. This study aimed …

Published: July 23, 2026, midnight
A rare case of life-threatening haematochezia in pregnancy associated with decidualized rectal mucosal endometriosis.

To report and emphasize the difficulty in diagnosis and management of acute gastrointestinal bleeding due to recurrent endometriosis in pregnancy.

Published: July 22, 2026, midnight
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