To apply an MR-PheWAS to infer causality between NSW and multiple health outcomes.
The present study aimed to determine the allelic and genotypic frequencies of the miRNA27a rs895819, miRNA222 rs2858060 and miRNA499 rs3746444 polymorphisms and their possible association with endometriosis. This case-control study …
Brazil recently implemented a national menstrual health program within its public health system (Sistema Único de Saúde [SUS]), representing a significant policy shift toward recognizing menstrual dignity as a public …
Daily activities, work, and health are closely intertwined. We closely followed 45 participants aged 50-66 years working across different sectors in a year-long study, who completed a range of baseline, …
Endometriosis is an estrogen-dependent chronic systemic inflammatory disease that affects 10 % of people assigned female at birth. Despite its prevalence, mean diagnostic delay is 4-11 years. Although much research …
Pediatric and Adolescent Gynecology (PAG) emerged to bridge gaps between pediatrics and adult gynecology, while pediatric surgeons currently provide most operative gynecologic care for young patients. The goal of this …
Endometriosis is a common gynecological disorder that requires accurate detection of ectopic lesions in laparoscopic images for effective diagnosis and treatment. However, existing deep learning-based detection methods face significant challenges …
Melatonin has evolved from its classical role as a pineal-derived circadian regulator to a molecule increasingly recognized for its mitochondrial and cytoprotective functions. This review examines the molecular mechanisms and …
Transcriptome-based drug repurposing can accelerate therapeutic discovery, but is limited by fragmented resources, inconsistent quality control, and reliance on single perturbation databases. We developed CDRPipe ( C omputational D rug …
Endometriosis (EMs) is a common gynecological disorder affecting reproductive‑aged women, characterized by ectopic endometrial growth and chronic pelvic pain that severely impairs quality of life. Although its pathogenesis remains incompletely …