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Opiranserin (VVZ-149): what's new in analgesics.

Opiranserin (VVZ-149) is a novel non-opioid, non-steroidal intravenous analgesic with triple antagonistic activity at glycine transporter 2 (GlyT2), purine 2 receptor 3 (P2X3), and serotonin receptor (5-HT2A). Its half-maximal inhibitory …

Published: Oct. 2, 2026, midnight
A novel approach to treating Endometriosis-Related Repeated IVF failures- insights from single case report.

This report explores the case of a young, normal-responder nulligravida with peritoneal endometriosis and recurrent implantation failure, with poor embryo quality during multiple failed attempts at IVF treatment. The patient …

Published: Sept. 24, 2026, midnight
Current Evidence and Emerging Directions in Endometriosis Pharmacotherapy: A Systematic Review of Recent Advances.

Background: Endometriosis affects 190 million women worldwide, so there is a need for accessible and more comprehensive knowledge regarding the pharmacotherapeutic options that can be offered to patients. This systematic …

Published: Sept. 17, 2026, midnight
Ectopic Endometrium-Targeted M1 Macrophage-Derived Nanovesicles for Treatment of Endometriosis.

Endometriosis (EMs) is a common gynecological disorder in women of reproductive age, often presenting with pelvic pain and infertility. Its progression is closely linked to estrogen levels. While hormonal therapies …

Published: Sept. 8, 2026, midnight
Achieving Minimal-to-No Pain in Women with Endometriosis Treated with Relugolix Combination Therapy: SPIRIT Extension Trial.

Relugolix is an oral, non-peptide gonadotropin-releasing hormone receptor antagonist administered as once-daily combination therapy (relugolix-CT; 40 mg relugolix, 1 mg estradiol, 0.5 mg norethindrone acetate) to reduce endometriosis symptoms while …

Published: Sept. 5, 2026, midnight
Choosing Between Newer GnRH Antagonist Therapies for Endometriosis - Patient Care Online

Choosing Between Newer GnRH Antagonist Therapies for Endometriosis Patient Care Online

Published: Aug. 26, 2026, 6:39 p.m.
Choosing Between Newer GnRH Antagonist Therapies for Endometriosis - Contemporary OB/GYN

Choosing Between Newer GnRH Antagonist Therapies for Endometriosis Contemporary OB/GYN

Published: Aug. 26, 2026, 12:10 p.m.
ATP-P2X3 Signaling as a Shared Neural Sensitization Pathway in Endometriosis and Irritable Bowel Syndrome: Mechanisms and Therapeutic Implications.

Endometriosis and irritable bowel syndrome (IBS) are chronic pain disorders that frequently coexist and share key pathophysiological features, including neuroinflammation, visceral hypersensitivity, peripheral sensitization, and central sensitization. Emerging evidence suggests …

Published: Aug. 25, 2026, midnight
Oral GnRH Antagonists Expand Choice, Not Cure - streamlinefeed.co.ke

Oral GnRH Antagonists Expand Choice, Not Cure streamlinefeed.co.ke

Published: Aug. 21, 2026, 7:12 a.m.
Comparing GnRH Agonists and Antagonists for Endometriosis Pain - Patient Care Online

Comparing GnRH Agonists and Antagonists for Endometriosis Pain Patient Care Online

Published: Aug. 19, 2026, 1:39 p.m.
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